Pular para o conteúdo
Merck
Todas as fotos(2)

Key Documents

View All Documentation

E0516

Sigma-Aldrich

Etodolac

Sinônimo(s):

1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid, Etodolic acid, NSC 282126

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(2)

About This Item

Fórmula empírica (Notação de Hill):
C17H21NO3
Número CAS:
41340-25-4
Peso molecular:
287.35
Número MDL:
MFCD00133313
Código UNSPSC:
12352200
ID de substância PubChem:
24278407
NACRES:
NA.77

Nível de qualidade

200

originador

Wyeth

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CCc1cccc2c3CCOC(CC)(CC(O)=O)c3[nH]c12

InChI

1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)

chave InChI

NNYBQONXHNTVIJ-UHFFFAOYSA-N

Informações sobre genes

human ... PTGS1(5742) , PTGS2(5743)

Procurando produtos similares? Visita Guia de comparação de produtos

Ações bioquímicas/fisiológicas

Non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX-1 and COX-2.

Características e benefícios

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Aplicação

Nº do produto
Descrição
Preços

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H301

Declarações de precaução

P264 - P270 - P301 + P310 - P405 - P501

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 4

1 of 4

Indometacina 98.5-100.5% (in accordance with EP)

Sigma-Aldrich

I7378

Indometacina

Diclofenac sodium salt

Sigma-Aldrich

D6899

Diclofenac sodium salt

Ibuprofen ≥98% (GC)

Sigma-Aldrich

I4883

Ibuprofen

Protease Type XIV, ≥3.5 units/mg solid, powder

Sigma-Aldrich

P5147

Protease

J A Balfour et al.
Drugs, 42(2), 274-299 (1991-08-01)
Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) effective in the treatment of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis, and in the alleviation of postoperative pain. Etodolac also provides relief of other types of pain, including that arising from gouty conditions
D C Brater et al.
Clinical rheumatology, 8 Suppl 1, 25-35 (1989-03-01)
The pharmacokinetics of etodolac, a new nonsteroidal anti-inflammatory drug, were compared in normal subjects, in patients with renal and hepatic disease, and in elderly patients. In 28 normal subjects, orally administered etodolac was rapidly absorbed. By 1.2 hours after ingestion
Shravan Kumar Tirunagari et al.
The Cochrane database of systematic reviews, (3)(3), CD007357-CD007357 (2009-07-10)
Etodolac is a selective cyclo-oxygenase-2 (COX-2) inhibitor, with evidence of efficacy in osteoarthritis and rheumatoid arthritis. Its analgesic efficacy in postoperative pain has not been clearly established. There are no systematic reviews on Etodolac's use in this condition. To assess
O Hazut et al.
International journal of clinical pharmacology and therapeutics, 49(9), 545-554 (2011-09-06)
COX inhibitors and β-adrenergic blockers were recently shown to reduce cancer progression in animal models through various mechanisms. These include the prevention of immune suppression during the critical perioperative period, and the preclusion of direct promoting effects of catecholamines and
N Zvaifler
Clinical rheumatology, 8 Suppl 1, 43-53 (1989-03-01)
Etodolac (Lodine, Ramodar, Ultradol), an anti-inflammatory, analgesic agent, is the first of a new class of nonsteroidal anti-inflammatory drugs (NSAIDs), the pyranocarboxylic acids. A review of the literature on numerous clinical studies showed that etodolac (200 to 600 mg/day) is
Exibir todos os documentos relacionados

Conteúdo relacionado

Discover Bioactive Small Molecules for Lipid Signaling Research

Discover Bioactive Small Molecules for Lipid Signaling Research

Chromatograms

application for HPLC

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica