D2629
6-(Dimethylamino)purine
≥98%
Sinônimo(s):
6-DMAP, N6,N6-Dimethyladenine
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About This Item
Fórmula empírica (Notação de Hill):
C7H9N5
Número CAS:
Peso molecular:
163.18
Beilstein:
7634
Número CE:
Número MDL:
Código UNSPSC:
41106305
ID de substância PubChem:
NACRES:
NA.51
Produtos recomendados
fonte biológica
synthetic (organic)
Ensaio
≥98%
Formulário
powder
pf
259-262 °C (lit.)
solubilidade
water: 50 mg/mL, clear to hazy, colorless to light yellow
temperatura de armazenamento
−20°C
cadeia de caracteres SMILES
CN(C)c1ncnc2[nH]cnc12
InChI
1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)
chave InChI
BVIAOQMSVZHOJM-UHFFFAOYSA-N
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Descrição geral
6-(Dimethylamino)purine (6-DMAP) is a purine-based metabolite with two condensed heterocyclic rings and two methyl groups linked to the amino group of the purine unit of adenine.
Aplicação
6-(Dimethylamino)purine has been used:
- as a supplement in GR-1 aa medium (bovine medium) for parthenogenetic activation of bovine oocytes to study its potential for embryo development
- in the activation step during the production of nuclear transfer embryos
- as a supplement in HCR2aa medium to activate interspecies embryos derived from interspecies somatic cell nuclear transfer (iSCNT) technique
Ações bioquímicas/fisiológicas
6-(Dimethylamino)purine (6-DMAP) is a protein kinase and cyclin-dependent kinase inhibitor. It acts as a secondary metabolite and mediates RNA modification. 6-DMAP is a potent cytokinetic inhibitor and is used in parthenogenesis and meiosis studies. It is also used to promote pronuclei formation in mammalian oocytes. 6-DMAP is a dual fluorescence molecule according to femtosecond fluorescence up-conversion spectroscopy studies.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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