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C8261

Sigma-Aldrich

Sodium chenodeoxycholate

≥97%

Sinônimo(s):

3α,7α-Dihydroxy-5β-cholanic acid, 5β-Cholanic acid-3α,7α-diol, Chenodeoxycholic acid sodium salt, Chenodesoxycholic acid, Chenodiol

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About This Item

Fórmula empírica (Notação de Hill):
C24H39NaO4
Número CAS:
2646-38-0
Peso molecular:
414.55
Número MDL:
MFCD00065452
Código UNSPSC:
12161900
ID de substância PubChem:
24893037
NACRES:
NA.25

descrição

anionic

Ensaio

≥97%

forma

powder

peso molecular

414.55 g/mol

técnica(s)

protein purification: suitable

cadeia de caracteres SMILES

[Na].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])CC[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(O)=O

InChI

1S/C24H40O4.Na.H/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);;/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-;;/m1../s1

chave InChI

WANBNZVOEKGHSS-VQNKLXGESA-N

Descrição geral

Sodium chenodeoxycholate is a bile salt, which has been shown to accelerate colonic transit and improve bowel function.

Aplicação

Sodium chenodeoxycholate has been used in a study to assess DNA repair response in the bacterium Escherichia coli. It has also been used in a study to investigate the physical and chemical factors influencing germination of Clostridium difficile spores.

Ações bioquímicas/fisiológicas

Bile Salt

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Frases de perigo

H301,H361d

Classificações de perigo

Acute Tox. 3 Oral - Repr. 2

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Colato de sódio suitable for cell culture, BioReagent

Sigma-Aldrich

C9282

Colato de sódio

Cholic Acid, Sodium Salt Primary bile acid.

Millipore

229101

Cholic Acid, Sodium Salt

Desoxicolato de sódio An ionic detergent for the solubilization of membrane-bound proteins.

Millipore

264101

Desoxicolato de sódio

Colato de sódio BioXtra, ≥99%

Sigma-Aldrich

C6445

Colato de sódio

Ursodeoxycholic acid ≥99%

Sigma-Aldrich

U5127

Ursodeoxycholic acid

Desoxicolato de sódio ≥97% (titration)

Sigma-Aldrich

D6750

Desoxicolato de sódio

Sodium glycochenodeoxycholate ≥97.0% (TLC)

Sigma-Aldrich

50534

Sodium glycochenodeoxycholate

Cholic acid from bovine and/or ovine, ≥98%

Sigma-Aldrich

C1129

Cholic acid

R L Kandell et al.
Nutrition and cancer, 16(3-4), 227-238 (1991-01-01)
Two bile salts, sodium chenodeoxycholate and sodium deoxycholate, induced a DNA repair response in the bacterium Escherichia coli. Similarly, a bile acid and a bile salt, chenodeoxycholic acid and sodium deoxycholate, induced DNA repair (indicated by unscheduled DNA synthesis) in
Sarinya Tawthep et al.
Journal of bioscience and bioengineering, 124(5), 514-522 (2017-07-29)
Understanding the dynamics of secondary bile acid (SBA) formation in the gut by SBA-producing bacteria is important for host health, as SBAs have been shown to affect host pathophysiology and gut microbiota composition. However, our knowledge of SBA producers is
L J Wheeldon et al.
Journal of applied microbiology, 105(6), 2223-2230 (2009-01-06)
To investigate the influence of chemical and physical factors on the rate and extent of germination of Clostridium difficile spores. Germination of C. difficile spores following exposure to chemical and physical germinants was measured by loss of either heat or
V Vanhoorne et al.
Orphanet journal of rare diseases, 14(1), 186-186 (2019-08-03)
Pharmaceutical compounding of orphan active ingredients can offer cost-effective treatment to patients when no other drug product is available for a rare disease or during periods of drug product shortages. Additionally, it allows customized therapy for patients with rare diseases.
Tina Kauss et al.
Journal of pharmaceutical sciences, 108(8), 2805-2813 (2019-03-18)
Current pediatric antibiotic therapies often use oral and parenteral routes of administration. Neither are suitable for treating very sick neonates who cannot take oral medication and may be several hours away from hospital in developing countries. Here, we report on
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