B7283

Benserazide hydrochloride

≥98% (HPLC), solid, L-aromatic amino acid decarboxylase inhibitor

• Sinônimo(s): DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
• Fórmula empírica (Notação de Hill): C₁₀H₁₅N₃O₅ · HCl
• Número CAS: 14919-77-8
• Peso molecular: 293.70
• Número CE: 238-991-9
• Número MDL: MFCD00078571
• Código UNSPSC: 12352125
• ID de substância PubChem: 24277886
• NACRES: NA.77

Propriedades

• product name: Benserazide hydrochloride, ≥98% (HPLC), solid
• fonte biológica: synthetic
• Ensaio: ≥98% (HPLC)
• forma: solid
• solubilidade: H₂O: 10 mg/mL
• originador: Roche
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: Cl.NC(CO)C(=O)NNCc1ccc(O)c(O)c1O
• InChI: 1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H
• chave InChI: ULFCBIUXQQYDEI-UHFFFAOYSA-N
• Informações sobre genes: human ... DDC(1644)

Descrição

Descrição geral

Benserazide is a peripheral decarboxylase inhibitor.

Aplicação

Benserazide has been used:

• to inhibit dopa-decarboxylase
• to induce dyskinesia
• to test on purified bacterial TDCs to assess the extent to which it could affect bacterial decarboxylases
• as a peripheral dopa decarboxylase inhibitor to treat mice

Ações bioquímicas/fisiológicas

Benserazide can block HK2 enzymatic activity in vitro. It is used along with levodopa to treat Parkinson′s disease.

Inhibitor of L-aromatic amino acid decarboxylase.

Características e benefícios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Outras notas

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves