A4034

L-ascorbato de (+)-sódio

powder, BioReagent, suitable for cell culture

• Sinônimo(s): Ácido L(+)-ascórbico, Vitamina C
• Fórmula empírica (Notação de Hill): C₆H₇NaO₆
• Número CAS: 134-03-2
• Peso molecular: 198.11
• Beilstein: 3767246
• Número CE: 205-126-1
• Número MDL: MFCD00082340
• Código UNSPSC: 12352205
• eCl@ss: 34058010
• ID de substância PubChem: 24890738
• NACRES: NA.75

Propriedades

• fonte biológica: synthetic (organic)
• Nível de qualidade: 200
• linha de produto: BioReagent
• Ensaio: ≥98%
• forma: powder
• peso molecular: M_w 135.13 g/mol
• técnica(s): cell culture | mammalian: suitable; cell culture | plant: suitable
• cor: white to off-white
• pf: 220 °C (dec.) (lit.)
• solubilidade: H₂O: 50 mg/mL
• cadeia de caracteres SMILES: [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]
• InChI: 1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1
• chave InChI: PPASLZSBLFJQEF-RXSVEWSESA-M

Descrição

Descrição geral

(+)-Sodium L-ascorbate (SA) is a potential antioxidant and is a derivative of vitamin C (L-ascorbic acid). It is widely used as a food additive. In addition, SA enhances growth retardation activity of bleomycin sulfate, R020-1724 (an inhibitor of cyclic nucleotide phosphodiesterase), prostaglandin E1 and sodium butyrate agents on neuroblastoma cells in culture. Elevated levels of SA induces two-stage urinary bladder carcinogenesis in rats. sodium L-ascorbate in combination with collagenogenesis inhibitors is used to treat dermal scars and keloids.

Aplicação

(+)-Sodium L-ascorbate has been used:

• to produce H₂O₂ in cell culture media
• as a reducing agent for a cell-permeable artificial electron donor, N,N,N′,N′-tetramethyl-p-phenylenediamine (TMPD)
• to study its effect on production of collagen and elastic fibers in fibroblasts cultures derived from normal human skin and dermal fat

Used for preparation of plant extracts; reductant for the isolation of chloroplasts.

Ações bioquímicas/fisiológicas

Antioxidant

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)