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Key Documents

47729

Sigma-Aldrich

N-Formyl-Met-Leu-Phe

BioXtra, ≥99.0% (TLC)

Sinônimo(s):

Chemotactic peptide, N-Formyl-L-methionyl-L-leucyl-L-phenylalanine, fMLF, fMLP (misnomer but widely used)

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About This Item

Fórmula empírica (Notação de Hill):
C21H31N3O5S
Número CAS:
Peso molecular:
437.55
Beilstein:
2315783
Número MDL:
Código UNSPSC:
12352209
ID de substância PubChem:

linha de produto

BioXtra

Nível de qualidade

Ensaio

≥99.0% (TLC)

forma

powder

cor

white

solubilidade

DMF: 50 mg/mL, clear, colorless

aplicação(ões)

cell analysis

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1

chave InChI

PRQROPMIIGLWRP-BZSNNMDCSA-N

Informações sobre genes

human ... FPR1(2357)

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Categorias relacionadas

Amino Acid Sequence

NFor-Met-Leu-Phe

Aplicação

1. 4th and 5th applications do not have access
2. 3rd application is not relevant

Ações bioquímicas/fisiológicas

N-Formyl-Met-Leu-Phe is a potent chemotactic peptide and formyl peptide receptor (FPR) agonist that induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.
Potent chemotactic peptide. Induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


Certificados de análise (COA)

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A D-methionine-containing peptide, Trp-Lys-Tyr-Met-Val-D-Met-NH(2) (WKYMVm), featuring a unique receptor specificity was investigated with respect to its ability to activate neutrophil effector functions. The peptide was found to be more potent than the N-formylated peptide N-formyl-Met-Leu-Phe (fMLF) at inducing neutrophil chemotaxis
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