46985
Fluorescein-5-thiosemicarbazide
suitable for fluorescence, ~80% (HPCE)
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About This Item
Fórmula empírica (Notação de Hill):
C21H15N3O5S
Número CAS:
Peso molecular:
421.43
Número MDL:
Código UNSPSC:
12352125
ID de substância PubChem:
NACRES:
NA.32
Produtos recomendados
Ensaio
~80% (HPCE)
Nível de qualidade
Formulário
solid
solubilidade
DMF: soluble
H2O: soluble
fluorescência
λex 492 nm; λem 516 nm in 0.1 M Tris pH 9.0
adequação
suitable for fluorescence
temperatura de armazenamento
−20°C
cadeia de caracteres SMILES
NNC(=S)Nc1ccc(c(c1)C(O)=O)C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24
InChI
1S/C21H15N3O5S/c22-24-21(30)23-10-1-4-13(16(7-10)20(27)28)19-14-5-2-11(25)8-17(14)29-18-9-12(26)3-6-15(18)19/h1-9,25H,22H2,(H,27,28)(H2,23,24,30)
chave InChI
MEUCHQDLZYLNQY-UHFFFAOYSA-N
Categorias relacionadas
Descrição geral
Fluorescein-5-thiosemicarbazide, also known as FTC, is a fluorescent probe. The FTSC fluorescent spectra is like FITC, a preferred fluorescent tag for proteomics. The fluorescence spectral properties of FTSC-labeled vesicles obtained by reductive amination are fully compatible with the argon laser of fluorescent instruments.
Aplicação
Fluorescein-5-thiosemicarbazide can be used as a fluorescent labeling reagent to label:
- Cell-surface functional groups (glycophorins) in the study of the effect of deoxygenation in the red blood cell membrane.
- Saccharides applicable in polysaccharide imaging in live cells.
- Chondroitin sulfate nanogels applicable in cell-specific drug delivery applications.
Características e benefícios
Fluorescein-5-thiosemicarbazide has the following benefits -
- It displays strong fluorescence property.
- Shows an intrinsic reactivity of the thiosemicarbazide group towards the aldehyde group.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Cholesterol plays important roles in biological membranes. The cellular location where cholesterol molecules work is prerequisite information for understanding their dynamic action. Bioimaging probes for cholesterol molecules would be the most powerful means for unraveling the complex nature of lipid
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We have used the fluorescence photobleaching recovery technique to study the dependence on oxygen tension of the lateral mobility of fluorescently labeled band 3, the phospholipid analogue fluorescein phosphatidylethanolamine, and glycophorins in normal red blood cell membranes. Band 3 protein
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Oxidative stress and inflammation play important roles in the pathogenesis of cardiovascular disease (CVD). Oxidative stress-induced desialylation is considered to be a primary step in atherogenic modification, and therefore, the attenuation of oxidative stress and/or inflammatory reactions may ameliorate CVD.
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