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Key Documents

42874

Sigma-Aldrich

Tetramethylrhodamine isothiocyanate–Dextran

average mol wt 40,000

Sinônimo(s):

TRITC-Dextran 40, TRITC-Dextran

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About This Item

Número MDL:
MFCD00132418
Código UNSPSC:
12352116
NACRES:
NA.32

fonte biológica

synthetic

forma

powder

peso molecular

average mol wt 40,000

Extensão da rotulagem

0.001-0.008 mol/mol TRITC glucose

fluorescência

λex 550 nm; λem 577 nm±5 nm in 0.1 M Tris pH 8.0

aplicação(ões)

cell analysis

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Descrição geral

Tetramethylrhodamine isothiocyanate–Dextran, also known as TRITC-Dextran or TRITC-Dextran 40, is a fluorescent dye and a novel drug. The fluorescent activity of TRITC-Dextran is detected at 555nm wavelength. The TRITC-Dextran molecules are released in the cells through passive diffusion due to a concentration gradient.

Aplicação

Tetramethylrhodamine isothiocyanate–Dextran (TRITC-Dextran 40) is used as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular drug delivery.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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J David Symons et al.
Arteriosclerosis, thrombosis, and vascular biology, 22(5), 772-780 (2002-05-15)
High circulating concentrations of homocysteine (ie, hyperhomocysteinemia [Hhcy]) impair the vascular function of peripheral conduit arteries and arterioles perfusing splanchnic and skeletal muscle regions. The effects of HHcy on coronary resistance vessel function and other indexes of vascular function, ie
Kimberley J Reeves et al.
Journal of vascular research, 49(2), 132-143 (2012-01-21)
This study evaluated four fluorescent-protein conjugates to monitor microcirculatory variables using the murine cremaster muscle and determined acute and long-term responses to repeated administration of FITC-BSA [conjugated at the University of Sheffield (UoS)] within a dorsal microcirculatory chamber (DMC) in
Andrea Kassner et al.
Neuroimaging clinics of North America, 21(2), 315-325 (2011-06-07)
The blood-brain barrier (BBB) is a functional concept to describe unique features of intracranial blood vessels that prevent many substances in the systemic circulation from entering the brain. In the setting of acute ischemic stroke, loss of blood-brain barrier (BBB)
Shuning Bian et al.
The Review of scientific instruments, 88(3), 034302-034302 (2017-04-05)
The development of a multimodal instrument capable of real-time in situ measurements of cavitation activity and effect in tissue mimicking phantoms during ultrasound and cavitation mediated drug delivery experiments is described here. The instrument features an acoustic arm that can
Alexa Patzelt et al.
Journal of controlled release : official journal of the Controlled Release Society, 246, 174-182 (2016-09-20)
More and more investigations confirm that nanoparticles are incapable of overcoming the intact skin barrier in vivo. Do nanoparticles still have a future in dermal drug delivery? Unlike many other topically applied substances, nanoparticles have not been reported to utilize
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Artigos

FITC-labelled polysaccharides

Additional information about FITC-labelled polysaccarides including FITC-Dextran, FITC-DEAE-dextran (FDD), FITC-carboxymethyl-dextran (FCM-Dextran). This page discusses the impact of weight-average molecular weight on the respective molecule dimensions and other physical properties

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