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346M-1

Sigma-Aldrich

Villin (CWWB1) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41
clone:
CWWB1, monoclonal
application:
IHC (p)
reatividade de espécies:
human
técnica(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
citations:
7

fonte biológica

mouse

Nível de qualidade

100
500

conjugado

unconjugated

forma do anticorpo

diluted ascites fluid

tipo de produto de anticorpo

primary antibodies

clone

CWWB1, monoclonal

descrição

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulário

buffered aqueous solution

reatividade de espécies

human

embalagem

vial of 0.1 mL concentrate (346M-14)
vial of 0.5 mL concentrate (346M-15)
bottle of 1.0 mL predilute (346M-17)
vial of 1.0 mL concentrate (346M-16)
bottle of 7.0 mL predilute (346M-18)

fabricante/nome comercial

Cell Marque™

técnica(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG1

controle

colon

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

visualização

cytoplasmic

Informações sobre genes

human ... VIL1(7429)

Categorias relacionadas

Descrição geral

Villin is a 95 kD glycoprotein of microvilli associated with rootlet formation in gastrointestinal mucosal epithelium. Anti-villin labels the brush border area in the gastrointestinal mucosal epithelium. This antibody has been useful in differentiating gastrointestinal adenocarcinoma, neuroendocrine carcinomas, and ovarian adenocarcinomas from adenocarcinomas of other organs. This antibody also labels Merkel cells of the skin.

Qualidade


IVD
IVD
IVD
RUO

Ligação

Villin Positive Control Slides, Product No. 346S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Certificados de análise (COA)

Lot/Batch Number
1509302A-Z
1434304A-Z

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Satoshi Nishizuka et al.
Cancer research, 63(17), 5243-5250 (2003-09-23)
Colon and ovarian cancers can be difficult to distinguish in the abdomen, and the distinction is important because it determines which drugs will be used for therapy. To identify molecular markers for that differential diagnosis, we developed a multistep protocol
P J Zhang et al.
Archives of pathology & laboratory medicine, 123(9), 812-816 (1999-08-24)
Villin, a 95-kd cytoskeletal protein associated with axial microfilament bundles of brush border microvilli, is mostly restricted to intestinal glandular tumors. Villin immunoexpression was recently observed in a small number of carcinoids of the intestinal tract and lung, but its
Sean K Lau et al.
Human pathology, 33(12), 1175-1181 (2003-01-07)
Distinguishing hepatocellular carcinoma (HCC) from cholangiocarcinoma (CC) and metastatic adenocarcinoma (MA) involving the liver can be problematic, often requiring the use of immunohistochemistry to facilitate diagnosis. Hep Par 1, a monoclonal antibody with expression confined primarily to benign and malignant
Robert W Werling et al.
The American journal of surgical pathology, 27(3), 303-310 (2003-02-27)
CDX2 is a recently cloned homeobox gene that encodes an intestine-specific transcription factor, expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. While expression of CDX2 protein in primary and metastatic colorectal carcinomas has been
J Tan et al.
Human pathology, 29(4), 390-396 (1998-05-01)
Villin (V) is a glycoprotein of microvilli associated with rootlet formation. Most colonic adenocarcinomas have a V positive (+), cytokeratin (CK) 20 (+), CK7-negative (-) immunophenotype; most lung adenocarcinomas have a CK20(-), CK7(+) immunophenotype. The reports of villin immunoreactivity in
Exibir todos os documentos relacionados

Artigos

Immunohistochemistry Applications in Gastrointestinal Cancer

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

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