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Documentos Principais

319R-2

Sigma-Aldrich

Cytokeratin 19 (EP72) Rabbit Monoclonal Primary Antibody

Sinônimo(s):

40-kDa keratin intermediate filament, CK-19, CK19, K19, K1CS, KRT 19, cytokeratin-19, keratin 19, type 1, keratin, type 1, 40-kd, keratin-19

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100
500

conjugado

unconjugated

forma do anticorpo

culture supernatant

tipo de produto de anticorpo

primary antibodies

clone

EP72, monoclonal

descrição

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulário

buffered aqueous solution

reatividade de espécies

human

embalagem

vial of 0.1 mL concentrate (319R-24)
vial of 0.1 mL concentrate Research Use Only (319R-24-RUO)
vial of 0.5 mL concentrate (319R-25)
vial of 1.0 mL concentrate (319R-26)
vial of 1.0 mL concentrate Research Use Only (319R-26-RUO)
vial of 1.0 mL pre-dilute Research Use Only (319R-27-RUO)
vial of 1.0 mL predilute ready-to-use (319R-27)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (319R-28-RUO)
vial of 7.0 mL predilute ready-to-use (319R-28)

fabricante/nome comercial

Cell Marque®

técnica(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)

Isotipo

IgG

controle

bladder, colon, colon carcinoma, thyroid carcinoma

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

visualização

cytoplasmic

Informações sobre genes

human ... KRT19(3880)

Descrição geral

Anti-cytokeratin 19 reacts with epithelia and epithelial malignancies including carcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Anti-cytokeratin 19 is very useful in differentiation of hepatocellular carcinoma from intrahepatic cholangiocarcinoma, especially in a combination of cytokeratin 7, CAM5.2, Ber-EP4/MOC31, Hep Par-1 and TTF1. Another useful application is the identification of thyroid papillary carcinoma.

Qualidade

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Ligação

Cytokeratin 19 Positive Control Slides, Product No. 319S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Predilute: diluted in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Concentrate: diluted in Phosphate Buffered Saline, pH 7.2, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

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Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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Juan Rosai
Tumori, 89(5), 517-519 (2004-02-12)
Immunohistochemical markers of thyroid tumors can be divided into two major categories: those related to the cell types and those related to the type of pathology. The most important markers in the first category are thyroglobulin and TTF-1 for follicular
Richa Jain et al.
Applied immunohistochemistry & molecular morphology : AIMM, 18(1), 9-15 (2009-12-04)
Cytokeratin immunostaining forms the bedrock of the immunohistochemical evaluation of tumors. Cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastroenteropancreatic and hepatobiliary tracts. CK19 immunohistochemistry has been used successfully in
Leandro Luongo de Matos et al.
Diagnostic pathology, 7, 97-97 (2012-08-15)
To distinguish between malignant and benign lesions of the thyroid gland histological demonstration is often required since the fine-needle aspiration biopsy method applied pre-operatively has some limitations. In an attempt to improve diagnostic accuracy, markers using immunocytochemistry and immunohistochemistry techniques

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