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Merck
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Key Documents

275R-1

Sigma-Aldrich

Ki-67 (SP6) Rabbit Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100
500

conjugado

unconjugated

forma do anticorpo

culture supernatant

tipo de produto de anticorpo

primary antibodies

clone

SP6, monoclonal

descrição

For In Vitro Diagnostic Use in Select Regions (See Chart)

forma

buffered aqueous solution

reatividade de espécies

human

embalagem

vial of 0.1 mL concentrate (275R-14)
vial of 0.5 mL concentrate (275R-15)
bottle of 1.0 mL predilute (275R-17)
vial of 1.0 mL concentrate (275R-16)
bottle of 7.0 mL predilute (275R-18)

fabricante/nome comercial

Cell Marque™

técnica(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG

controle

tonsil

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

visualização

nuclear

Informações sobre genes

human ... MKI67(4288)

Categorias relacionadas

Descrição geral

The Ki-67 antigen is a nuclear, non-histone protein that is present in proliferatingcells. Though its specific role is largely postulated and still yet to be determined,Ki-67’s presence during cellular division makes it an excellent target for labeling rapidlygrowing malignancies. Given that its presence correlates with cell proliferation, theimmunohistochemical labeling of Ki-67 antigen may be useful in characterizing a lesion’sgrowth fraction.

Qualidade


IVD
IVD
IVD
RUO

Ligação

Ki-67 Positive Control Slides, Product No. 275S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Swerdlow S, et al. WHO clarifications of tumours of hematopoietic and lymphoid tissues. 4th edition, 2008. P 220.
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 220-220 (2008)
P E McKeever et al.
Journal of neuropathology and experimental neurology, 57(10), 931-936 (1998-10-24)
The purpose of this study was to determine whether a relationship existed between MIB-1 labeling index (LI) percentages and survival in patients with grade II astrocytomas. From archival paraffin-embedded surgical specimens of 50 patients of the University of Michigan Medical
S W Coons et al.
Neurosurgery, 41(4), 878-884 (1997-10-08)
The prognostic significance of quantitative measurement of tumor proliferative activity was evaluated for oligodendroglial tumors. Ki-67/MIB-1 immunochemistry was used to measure proliferative activity in 81 oligodendrogliomas and oligoastrocytomas. The relationship among survival, proliferation, histological features, and clinical variables were evaluated
Ran Marciano et al.
Cancers, 11(2) (2019-02-02)
Tumor cells utilize glucose to fuel their anabolic needs, including rapid proliferation. However, due to defective vasculature and increased glucose uptake, tumor cells must overcome glucose deprivation. Accordingly, tumor cells depend on cellular pathways promoting survival under such conditions. Targeting
Carmen J Allegra et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 21(2), 241-250 (2003-01-15)
To define the value of thymidylate synthase (TS), Ki-67, and p53 as prognostic markers in patients with stage II and III colon carcinoma. We retrospectively analyzed the prognostic value of TS, Ki-67, and p53 in 706 patients with Dukes' B
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Diagnostic immunohistochemistry overview highlights its importance in cancer diagnosis and detecting infectious diseases in modern clinical pathology.

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