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Documentos Principais

234A-1

Sigma-Aldrich

hCG Rabbit Polyclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100
500

conjugado

unconjugated

forma do anticorpo

Ig fraction of antiserum

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

descrição

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulário

buffered aqueous solution

reatividade de espécies

human

embalagem

vial of 0.1 mL concentrate (234A-14)
vial of 0.5 mL concentrate (234A-15)
bottle of 1.0 mL predilute (234A-17)
vial of 1.0 mL concentrate (234A-16)
bottle of 7.0 mL predilute (234A-18)

fabricante/nome comercial

Cell Marque®

técnica(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:250

controle

placenta

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

visualização

cytoplasmic

Informações sobre genes

human ... NUP42(11097)

Descrição geral

Human chorionic gonadotropin (hCG) is a hormone synthesized by syncytiotrophoblasts and belongs to a group of glycoprotein hormones known as gonadotropins. Gonadotropins regulate normal growth, sexual development, and reproductive function. This antibody detects syncytiotrophoblasts in placenta and in tumors such as choriocarcinoma and some cases of seminoma.
hCG is a protein secreted in large quantities by normal trophoblasts; the antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive for anti-hCG. hCG expression by non-trophoblastic tumors may indicate aggressive behavior since it has been observed that hCG may play a role in the host response to a given tumor.

Qualidade


IVD

IVD

IVD

RUO

Ligação

hCG Positive Control Slides, Product No. 234S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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L D Boucher et al.
Human pathology, 26(11), 1201-1206 (1995-11-01)
The authors studied the expression of trophoblastic cell markers in lung carcinomas cells by immunoperoxidase staining using antibodies against three trophoblastic glycoproteins (human chorionic gonadotropin [hCG]; human placental lactogen [hPL]; pregnancy-specific beta 1-glycoprotein [SP-1]). One hundred five tissue sections from
R J Kurman et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 3(1), 101-121 (1984-01-01)
This report presents preliminary observations on the immunocytochemical localization of human chorionic gonadotropin (hCG) and human placental lactogen (hPL) in placental site trophoblastic tumors, hydatidiform moles, and choriocarcinomas and compares the findings with those of a similar immunocytochemical analysis of
Choriogonadotropin positive seminoma-a clinicopathological and molecular genetic study of 15 cases.
Hes, Ondrej et al
Annals of diagnostic pathology, 18,2, 89-94 (2014)
W L Davis et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 35(1), 39-48 (1987-01-01)
The calcium-regulating enzyme calcium adenosine triphosphatase (Ca-ATPase) was localized in the epithelium of amphibian urinary bladder by the one-step electron microscopic cytochemical procedure. The enzyme was identified along the basolateral border of the epithelial cells that comprise the bladder mucosa.
Determination of biological activity of gonadotropins hCG and FSH by Forster resonance energy transfer based biosensors.?
Mazina, Olga et al.
Scientific Reports, 7, 42219-42219 (2017)

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