229A-1

Calcitonin Rabbit Polyclonal Antibody

• Código UNSPSC: 12352203
• NACRES: NA.41
• clone: polyclonal
• application: IHC (p)
• reatividade de espécies: human
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200-1:1000
• citations: 5

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100; 500
• conjugado: unconjugated
• forma do anticorpo: Ig fraction of antiserum
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• descrição: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formulário: buffered aqueous solution
• reatividade de espécies: human
• embalagem: vial of 0.1 mL concentrate (229A-14); vial of 0.5 mL concentrate (229A-15); bottle of 1.0 mL predilute (229A-17); vial of 1.0 mL concentrate (229A-16); bottle of 7.0 mL predilute (229A-18)
• fabricante/nome comercial: Cell Marque^™
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200-1:1000
• controle: medullary carcinoma of thyroid
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• visualização: cytoplasmic

Descrição

Descrição geral

Calcitonin (thyrocalcitonin) is a 32 amino acid linear polypeptide hormone that is involved in regulating calcium metabolism. It is primarily produced by the parafollicular cells (also known as C cells) of the thyroid gland, though some neuroendocrine cells in other tissues, such as the respiratory and digestive tracts, can also synthesize calcitonin. Anti-calcitonin immunohistochemistry is an effective way for demonstrating the parafollicular C cells in the thyroid and the tumors arising from them, including C cell hyperplasia of the thyroid and medullary thyroid carcinoma, a neuroendocrine tumor that originates from C cells.
Immunohistochemical staining with anti-calcitonin antibodies has proven to be an effective way of demonstrating calcitonin-producing cells in the thyroid. C-cell hyperplasia and medullary thyroid carcinomas stain positive for calcitonin. Studies of calcitonin have resulted in the identification of a wide spectrum of C-cell proliferative abnormalities.

Ligação

Calcitonin Positive Control Slides, Product No. 229S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

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Outras notas

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Informações legais

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany