Y0001601

Alfacalcidol for system suitability

European Pharmacopoeia (EP) Reference Standard

• Sinônimo(s): 1α-Hydroxyvitamin D₃, 1α-Hydroxycholecalciferol, Alfacalcidol
• Fórmula empírica (Notação de Hill): C₂₇H₄₄O₂
• Número CAS: 41294-56-8
• Peso molecular: 400.64
• Número MDL: MFCD00868328
• Código UNSPSC: 41116107
• ID de substância PubChem: 329831506
• NACRES: NA.24

Propriedades

• fonte biológica: synthetic
• grau: pharmaceutical primary standard
• Agency: EP
• forma: solid
• fabricante/nome comercial: EDQM
• técnica(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C
• InChI: 1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1
• chave InChI: OFHCOWSQAMBJIW-AVJTYSNKSA-N
• Informações sobre genes: human ... VDR(7421)

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Ações bioquímicas/fisiológicas

Synthetic vitamin D₃ analog that is metabolized to 1,25-dihydroxycholecalciferol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H300
• Declarações de precaução: P301 + P330 + P331 + P310
• Classificações de perigo: Acute Tox. 1 Oral
• Código de classe de armazenamento: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable