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Y0000108

Trihexyphenidyl hydrochloride

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

(±)-α-Cyclohexyl-α-phenyl-1-piperidinepropanol hydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C20H31NO · HCl
Número CAS:
52-49-3
Peso molecular:
337.93
Número MDL:
MFCD00058212
Código UNSPSC:
41116107
ID de substância PubChem:
329830848
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

trihexyphenidyl hydrochloride

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Cl.OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3

InChI

1S/C20H31NO.ClH/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21;/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2;1H

chave InChI

QDWJJTJNXAKQKD-UHFFFAOYSA-N

Informações sobre genes

human ... CHRM1(1128)

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Trihexyphenidyl hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

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The Journal of the Association of Physicians of India, 59, 526-527 (2011-09-06)
We report a 42 year-old woman with 6 month history of isolated lingual dystonia induced during speaking and was treated with anticholinergic drug. She experienced a marked improvement in her abnormal tongue movements. Primary lingual dystonia is a rare presentation.
Joana Damásio et al.
Movement disorders : official journal of the Movement Disorder Society, 26(4), 679-684 (2011-04-21)
The co-occurrence of tics and dystonia as an idiopathic condition has only rarely been reported. We report a series of patients with tics and persistent dystonia, with the aim of determining the prevalence and clinical characteristics of this syndrome. Analysis
Computer mouse-related dystonia: a novel presentation of task-specific dystonia.
Keisuke Suzuki et al.
Journal of neurology, 259(10), 2221-2222 (2012-05-10)
Sushma Sonavane et al.
The journal of ECT, 28(1), 48-49 (2011-10-11)
Transient, postictal cortical blindness is a rare adverse effect of electroconvulsive therapy (ECT). There is no information on the safety of continuation of ECT in patients who recover from ECT-induced cortical blindness. An 18-year-old woman with paranoid schizophrenia experienced cortical
Bradley James Robottom et al.
The neurologist, 17(6), 340-341 (2011-11-03)
Trihexyphenidyl is 1 of the most effective agents for treatment of young-onset dystonia. As such, women of childbearing potential use trihexyphenidyl despite inadequate information about potential effects on pregnancy, labor, and fetal development. We report 2 uncomplicated pregnancies in 1
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