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Y0000022

Sumatriptan succinate

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate, GR-43175

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About This Item

Fórmula empírica (Notação de Hill):
C14H21N3O2S · C4H6O4
Número CAS:
103628-48-4
Peso molecular:
413.49
Número MDL:
MFCD00902856
Código UNSPSC:
41116107
ID de substância PubChem:
329830818
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

sumatriptan

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

InChI

1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

chave InChI

PORMUFZNYQJOEI-UHFFFAOYSA-N

Informações sobre genes

human ... HTR1B(3351) , HTR1D(3352)

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Sumatriptan succinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Ações bioquímicas/fisiológicas

Sumatriptan succinate is a 5-HT1 serotonin receptor agonist.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

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Sumatriptan for system suitability, European Pharmacopoeia (EP) Reference Standard

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Sumatriptan succinate, British Pharmacopoeia (BP) Reference Standard

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Sumatriptan Succinate, pharmaceutical secondary standard, certified reference material

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Pictogramas

Health hazard
GHS08

Palavra indicadora

Warning

Frases de perigo

H361d,H412

Classificações de perigo

Aquatic Chronic 3 - Repr. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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Christian Asseburg et al.
International journal of technology assessment in health care, 28(4), 382-389 (2012-09-28)
The cost-effectiveness of triptans in the treatment of migraine has not been assessed since generic sumatriptan entered the Finnish market in 2008. Using systematic review and mixed treatment comparison, the effectiveness of triptans was estimated with regard to 2-hour response
Daxesh P Patel et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 902, 122-131 (2012-07-24)
An ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method has been developed for the simultaneous determination of sumatriptan and naproxen in human plasma using naratriptan and indomethacin as the internal standards (ISs). The plasma samples were prepared by solid phase
Benjamin W Friedman et al.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 19(10), 1151-1157 (2012-09-22)
Patients who use an emergency department (ED) for acute migraine headaches have higher migraine disability scores, lower socioeconomic status, and are unlikely to have used a migraine-specific medication prior to presentation to the ED. The objective was to determine if
Toshihiko Tomita et al.
Journal of gastroenterology and hepatology, 28(1), 106-111 (2012-09-20)
Scintigraphy is a useful noninvasive technique for assessment of gastric motility, especially emptying, but there is little knowledge of use of the technique to assess gastric accommodation. Therefore, to clarify the usefulness of scintigraphy as a technique for assessing gastric
Maria Luisa González-Rodríguez et al.
Journal of pharmaceutical sciences, 101(10), 3845-3863 (2012-07-19)
Niosomes formulated from different nonionic surfactants (Span® 60, Brij® 72, Span® 80, or Eumulgin® B 2) with cholesterol (CH) molar ratios of 3:1 or 4:1 with respect to surfactant were prepared with different sumatriptan amount (10 and 15 mg) and
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