SMB00953

2-Cyano-3,3-diphenylacrylic acid

≥95%

• Sinônimo(s): α-Cyano-β-diphenylacrylic acid, 2-Cyano-3,3-diphenylpropenoic acid
• Fórmula empírica (Notação de Hill): C₁₆H₁₁NO₂
• Número CAS: 10380-41-3
• Peso molecular: 249.26
• Código UNSPSC: 12352106
• NACRES: NA.22

Propriedades

• fonte biológica: synthetic
• Nível de qualidade: 200
• Ensaio: ≥95%
• forma: solid
• peso molecular: 249.26 g/mol
• condição de armazenamento: (Tightly closed. Dry.)
• técnica(s): HPLC: suitable
• cor: white to off-white
• temperatura de armazenamento: 2-8°C
• InChI: 1S/C16H11NO2/c17-11-14(16(18)19)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H,(H,18,19)
• chave InChI: VSXIZXFGQGKZQG-UHFFFAOYSA-N

Descrição

Descrição geral

2-Cyano-3,3-diphenylacrylic acid (CDA) belongs to the class of α,β-unsaturated carboxylic acids. It is a primary metabolite of Octocrylene, an organic sunscreen that functions by absorbing UVB radiation and short UVA wavelengths, commonly utilized in cosmetics for sun protection. CDA exhibits prolonged systemic availability after dermal exposure which may accumulate in the body. It can be used to study skin-permeable selective cyclooxygenaswe-2 inhibitor composition, and to study hydrophilic components of cosmetic compositions, such as in sunscreen.

Aplicação

2-Cyano-.3-diphenylacrylic acid finds application in metabolomics, cosmetics and cancer research

Ações bioquímicas/fisiológicas

Within the human body, Octocrylene, a non-polar compound, undergoes metabolism to become a water-soluble metabolite 2-cyano-3,3-diphenylacrylic acid, which is excreted through the kidneys. A pilot study in the general population has consistently detected CDAA, and its levels have been linked to recent sunscreen application.

Características e benefícios

• High quality compound suitable for multiple research applications
• Compatible with a wide variety of chromatographic and spectrometry techniques

Outras notas

For additional information on our range of Biochemicals, please complete this form.

This product is intended for research purposes only, and it is not meant for human consumption.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable