PHR3250

Thioguanine

pharmaceutical secondary standard, certified reference material

• Sinônimo(s): 6-Thioguanine, 2-Amino-6-mercaptopurine, 2-Amino-6-purinethiol
• Fórmula empírica (Notação de Hill): C₅H₅N₅S
• Número CAS: 154-42-7
• Peso molecular: 167.19
• Beilstein: 157765
• Número MDL: MFCD00233553
• Código UNSPSC: 41116107

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to USP 1660000
• família API: tioguanine, thioguanine
• Certificado de análise (CofA): current certificate can be downloaded
• embalagem: pkg of 500 mg
• pf: ≥300 °C (lit.)
• aplicação(ões): pharmaceutical
• temperatura de armazenamento: -10 to -25°C
• cadeia de caracteres SMILES: NC1=Nc2nc[nH]c2C(=S)N1
• InChI: 1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
• chave InChI: WYWHKKSPHMUBEB-UHFFFAOYSA-N

Descrição

Descrição geral

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Aplicação

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Ações bioquímicas/fisiológicas

Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H301
• Declarações de precaução: P264 - P270 - P301 + P310 - P405 - P501
• Classificações de perigo: Acute Tox. 3 Oral
• Código de classe de armazenamento: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable