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Documentos Principais

PHR1955

Supelco

Mepivacaine hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Mepivacaine hydrochloride, 1-Methyl-2′,6′-pipecoloxylidine hydrochloride, N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C15H22N2O · HCl
Número CAS:
Peso molecular:
282.81
Número CE:
Número MDL:
Código UNSPSC:
41116107
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to BP 699
traceable to Ph. Eur. M0370000
traceable to USP 1387002

família API

mepivacaine

Certificado de análise (CofA)

current certificate can be downloaded

embalagem

pkg of 500 mg

aplicação(ões)

pharmaceutical

Formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

CN1CCCCC1C(NC2=C(C)C=CC=C2C)=O.Cl

InChI

1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H

chave InChI

RETIMRUQNCDCQB-UHFFFAOYSA-N

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Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mepivacaine hydrochloride is a local anesthetic that is related chemically and pharmacologically to the amide-type local anesthetics. It is often administered via local infiltration, peripheral nerve block, etc.

Aplicação

Mepivacaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Ações bioquímicas/fisiológicas

Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current.
Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB1955 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Pictogramas

Skull and crossbones

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 3 Oral - STOT SE 3

Órgãos-alvo

Central nervous system

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Certificados de análise (COA)

Lot/Batch Number

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Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

The Estimation of Mepivacain Hydrochloride Injection Liquid
Hazarathaiah C
International Journal of Engineering and Techniques null
Mepivacaine hydrochloride
USP42-NF37
United States Pharmacopeia/National Formulary, 38(6), 2743-2743 (2018)
Determination of local anaesthetics and their impurities in pharmaceutical preparations using HPLC method with amperometric detection
Fijalek Z, et al.
Journal of Pharmaceutical and Biomedical Analysis, 37(5), 913-918 (2005)

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