PHR1828

Eucalyptol (cineole)

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): Eucalyptol, 1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane, 1,8-Cineole, 1,8-Epoxy-p-menthane
• Fórmula empírica (Notação de Hill): C₁₀H₁₈O
• Número CAS: 470-82-6
• Peso molecular: 154.25
• Beilstein: 105109
• Número CE: 207-431-5
• Número MDL: MFCD00167977
• Código UNSPSC: 12352212
• ID de substância PubChem: 329823628
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to Ph. Eur. Y0000176; traceable to USP 1268900
• família API: cineole
• Certificado de análise (CofA): current certificate can be downloaded
• embalagem: pkg of 500 mg
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• índice de refração: n20/D 1.457 (lit.)
• p.e.: 176-177 °C (lit.)
• pf: 1-2 °C (lit.)
• densidade: 0.921 g/mL at 25 °C (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: C[C@]12CC[C@H](CC1)C(C)(C)O2
• InChI: 1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3/t8-,10+
• chave InChI: WEEGYLXZBRQIMU-WAAGHKOSSA-N

Descrição

Descrição geral

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Eucalyptol, a natural monoterpene, is a component of many medicinally active aromatic plants, such as eucalyptus, cardamom, thyme, rosemary, and ginger. It exhibits subduing effect on mucus hypersecretion, non-purulent rhinosinusitis, and asthma.

Aplicação

This pharmaceutical secondary standard can also be used as follows:

• Simultaneous estimation of menthol and eucalyptol in their combined marketed analgesic formulations by high-performance thin layer chromatography (HPTLC) procedure
• The development of an International Conference on Harmonization (ICH) guideline validated HPTLC method for the determination of α-pinene and eucalyptol in plants from the Lamiaceae family
• Headspace sorptive extraction (HSSE) of seven monoterpenes for their gas chromatography and mass spectrometry (GC-MS) based quantitative analysis from different honey samples
• Screening and estimation of eucalyptol in a polyherbal formulation using an HPTLC-based technique

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB9507 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações de segurança

• Pictogramas: GHS02,GHS07
• Palavra indicadora: Warning
• Frases de perigo: H226,H317
• Declarações de precaução: P210 - P233 - P240 - P241 - P280 - P303 + P361 + P353
• Classificações de perigo: Flam. Liq. 3 - Skin Sens. 1
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 125.6 °F - closed cup
• Ponto de fulgor (°C): 52 °C - closed cup