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Key Documents

PHR1577

Supelco

Sulfamerazine

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Sulfamerazine, 4-Amino-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide, N1-(4-Methylpyrimidin-2-yl)sulfanilamide

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About This Item

Fórmula empírica (Notação de Hill):
C11H12N4O2S
Número CAS:
Peso molecular:
264.30
Beilstein:
249133
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to Ph. Eur. S2000000
traceable to USP 1628007

família API

sulfamerazine

Certificado de análise (CofA)

current certificate can be downloaded

embalagem

pkg of 1 g

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1

InChI

1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

chave InChI

QPPBRPIAZZHUNT-UHFFFAOYSA-N

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Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sulfamerazine belongs to the class of sulfonamides, used as an antibacterial agent to treat infections, especially for patients intolerant to antibiotics.

Aplicação

Sulfamerazine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophototmetric technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA4493 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Visite a Biblioteca de Documentos

A sensitive spectrophotometric method for the determination of sulfonamides in pharmaceutical preparations
Nagaraja P, et al.
Acta pharmaceutica, 57(3), 333-342 (2007)
Marco De Liguoro et al.
Ecotoxicology and environmental safety, 164, 84-91 (2018-08-12)
In livestock farming, sulfonamides (SAs) are used prophylactically and simultaneously in large numbers of animals. Therefore, traces of these compounds, alone or in combination, have been repeatedly detected in the environment. Synergistic interactions among chemicals in such mixtures represent an
Padmarjaiah Nagaraja et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 53(2), 187-192 (2002-03-07)
A rapid, selective and simple spectrophotometric method for the determination of sulfa-drugs is described. The method is based on the formation of violet colored azo product by the diazotization of sulfonamides, viz. sulfathiazole (SFT), sulfadiazine (SFD), sulfacetamide (SFA), sulfamethoxazole (SFMx)

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