PHR1494

Pilocarpine Nitrate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): Pilocarpine nitrate salt
• Fórmula empírica (Notação de Hill): C₁₁H₁₆N₂O₂ · HNO₃
• Número CAS: 148-72-1
• Peso molecular: 271.27
• Beilstein: 4171406
• Número CE: 205-723-7
• Número MDL: MFCD00078497
• Código UNSPSC: 41116107
• ID de substância PubChem: 329823416
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to BP 503; traceable to Ph. Eur. P1700000; traceable to USP 1539009
• família API: pilocarpine
• Certificado de análise (CofA): current certificate can be downloaded
• embalagem: pkg of 500 mg
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
• InChI: 1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1
• chave InChI: PRZXEPJJHQYOGF-GNAZCLTHSA-N
• Informações sobre genes: human ... CHRM1(1128) , CHRM3(1131)

Descrição

Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pilocarpine Nitrate is a naturally occurring cholinomimetic drug, exhibiting nicotinic and muscarinic properties. It is widely used for controlling intraocular pressure in glaucoma, immediate relief of mydriasis, and to reverse mydriasis caused by cycloplegic agents.

Aplicação

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Ações bioquímicas/fisiológicas

Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA3042 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informações de segurança

• Pictogramas: GHS03,GHS06
• Palavra indicadora: Danger
• Frases de perigo: H272,H302,H330
• Declarações de precaução: P210 - P220 - P260 - P264 - P301 + P312 - P304 + P340 + P310
• Classificações de perigo: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Ox. Sol. 2
• Código de classe de armazenamento: 5.1B - Oxidizing hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable