PHL89262

Quercetina

phyproof^® Reference Substance

• Sinônimo(s): 2-(3,4-di-hidroxifenil)-3,5,7-tri-hidroxi-4H-1-benzopiran-4-ona, 3,3′,4′,5,6-penta-hidroxiflavona
• Fórmula empírica (Notação de Hill): C₁₅H₁₀O₇
• Número CAS: 117-39-5
• Peso molecular: 302.24
• Beilstein: 317313
• Código UNSPSC: 41116107
• NACRES: NA.24

Propriedades

• grau: primary reference standard
• linha de produto: phyproof^® Reference Substance
• Ensaio: ≥95.0% (HPLC)
• fabricante/nome comercial: PhytoLab
• aplicação(ões): food and beverages
• formato: neat
• cadeia de caracteres SMILES: OC1=CC(O)=C2C(OC(C3=CC=C(O)C(O)=C3)=C(O)C2=O)=C1
• InChI: 1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
• chave InChI: REFJWTPEDVJJIY-UHFFFAOYSA-N

Descrição

Descrição geral

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Aplicação

• Simultaneous determination of eight arginine-related metabolites in cellular extracts using liquid chromatography-tandem mass spectrometry.: This study utilized the Chromolith^® RP-18 endcapped column to achieve high-resolution separation of arginine-related metabolites in cellular extracts. The method demonstrated excellent reproducibility and sensitivity, highlighting the column′s effectiveness in complex biological sample analysis (Amatya S et al., 2020).


• Rapid Determination of 30 Polyphenols in Tongmai Formula, a Combination of Puerariae Lobatae Radix, Salviae Miltiorrhizae Radix et Rhizoma, and Chuanxiong Rhizoma, via Liquid Chromatography-Tandem Mass Spectrometry.: The Chromolith^® RP-18 endcapped column was employed for the rapid and efficient determination of polyphenols in a traditional Chinese medicine formula. The column′s high throughput and robust performance facilitated the simultaneous analysis of multiple compounds, demonstrating its application in natural product research (Wang FR et al., 2017).


• Simultaneous Liquid Chromatographic Determination of Ebastine with Two Sympathomimetic Drugs Using a Monolithic Column.: This research applied the Chromolith^® RP-18 endcapped column to the simultaneous chromatographic determination of ebastine and two sympathomimetic drugs. The study underscored the column′s ability to provide rapid and efficient separations in pharmaceutical analysis, ensuring accurate quantification of drug components (Ibrahim F et al., 2017).

Ações bioquímicas/fisiológicas

A quercetina é um flavonoide com atividade antineoplásica. A quercetina é um inibidor de ATPase e fosfodiesterase mitocondrial. Inibe a atividade da PI3-quinase e inibe ligeiramente a atividade da PIP quinase. A quercetina tem efeitos antiproliferativos nas linhagens celulares cancerosas, reduz o crescimento de células cancerosas através dos receptores de estrogênio tipo II e detém as células T leucêmicas humanas na fase G1 tardia do ciclo celular. A quercetina também pode inibir a atividade da ácido graxo sintase.

Outras notas

This compound is commonly found in plants of the genus: allium angelica arnica glycyrrhiza hypericum lycium sambucus

Informações legais

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H301
• Declarações de precaução: P264 - P270 - P301 + P310 - P405 - P501
• Classificações de perigo: Acute Tox. 3 Oral
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3