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Documentos Principais

00180585

Hyperoside

primary reference standard

Sinônimo(s):

Quercetin 3-D-galactoside, 3,3′,4′,5,7-Pentahydroxyflavone 3-D-galactoside, Hyperin, Hyperoside

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About This Item

Fórmula empírica (Notação de Hill):
C21H20O12
Número CAS:
Peso molecular:
464.38
Beilstein:
5784795
Número CE:
Número MDL:
Código UNSPSC:
85151701
ID de substância PubChem:
NACRES:
NA.24

grau

primary reference standard

prazo de validade

limited shelf life, expiry date on the label

fabricante/nome comercial

HWI

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

cadeia de caracteres SMILES

OC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1

chave InChI

OVSQVDMCBVZWGM-DTGCRPNFSA-N

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Descrição geral

Hyperoside is a flavonol glycoside compound used in Traditional Chinese medicine for its various beneficial effects, such as anti-inflammatory, anti-oxidant, anti-viral, and anti-cancer.
Produced and qualified by HWI pharma services GmbH.
Exact content measured by quantitative NMR can be found on the certificate.

Aplicação

The primary reference standard can be used for identification, assay, and purity testing, method development, and validation.

It can also be used as follows:

  • Development of an ultra performance liquid chromatography-mass spectrometric method to determine hyperoside in rat plasma samples following sample treatment by protein precipitation and liquid-liquid extraction
  • Multi-residue analysis of hyperoside, isoquercitrin, and eleutheroside E in botanical samples of Apocynum venetum L. and Eleutherococcus senticosus used in traditional Chinese medicine by HPLC combined with diode array detection (DAD)
  • Ionic liquid vacuum microwave-assisted extraction (ILVMAE) of rutin, hyperoside, and hesperidin from Sorbus tianschanica leaf samples for their subsequent quantification by HPLC
  • Simultaneous detection and quantification of vitexin, rutin, hyperoside, and quercetin in hawthorn flower and leaf extract samples using high-performance liquid chromatography combined with spectrophotometric detection (HPLC-UV)

Ações bioquímicas/fisiológicas

Protects against peroxide-induced oxidative damage to cells by scavenging reactive oxygen species and enhancing activity of anti-oxidant enzymes, in particular, catalase and glutathione peroxidase.

Outras notas

A flavonol glycoside widely distribute in plants, including mimosa and St. John′s wort.
This compound is commonly found in plants of the genus: crataegus eucalyptus hypericum sambucus

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Certificados de análise (COA)

Lot/Batch Number

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Isorhamnetin 3-rutinoside phyproof® Reference Substance

PHL83337

Isorhamnetin 3-rutinoside

Quercitrin European Pharmacopoeia (EP) Reference Standard

Y0001931

Quercitrin

Rutin trihydrate analytical standard

Supelco

78095

Rutin trihydrate

Quercetin 3-glucoside analytical standard

Supelco

16654

Quercetin 3-glucoside

Isovitexin ≥98.0% (HPLC)

Sigma-Aldrich

17804

Isovitexin

Sae-Kwang Ku et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 53, 197-204 (2012-12-12)
The potential anticoagulant activities of two single compounds, isorhamnetin-3-O-galactoside (IMG) and hyperoside, from Oenanthe javanica, were tested. The anticoagulant activities were investigated by measuring activated partial thromboplastin time (aPTT) and prothrombin time (PT), and the ability to inhibit production of
Xi-Hua Cui et al.
Bioresource technology, 102(21), 10072-10079 (2011-09-16)
The effects of inoculum density, aeration volume and culture period on accumulation of biomass and secondary metabolites in adventitious roots of Hypericum perforatum in balloon type airlift bioreactors (3 l capacity) were investigated. The greatest increment of biomass as well
Lei Zhou et al.
Journal of medicinal food, 15(5), 461-468 (2012-03-24)
Diabetic nephropathy (DN) is an important diabetic complication, and podocyte apoptosis plays a critical role in the development of DN. In the present study, we examined the preventive effect of the total flavone glycosides of Flos Abelmoschus manihot (TFA) on
Jianming Guo et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(14), 1250-1254 (2011-07-26)
Depression is the most common psychiatric comorbidity in patients with epilepsy. Searching for antiepileptic (anticonvulsant) and antidepressant-like medicines from natural products is very important for the treatment of this disease. The flower of Abelmoschus manihot (Linn.) Medicus has been reported
Anti-inflammatory activity of hyperoside through the suppression of nuclear factor-?B activation in mouse peritoneal macrophages.
Kim SJ, Um JY, Lee JY
American Journal of Chinese Medicine, 39(1), 171-181 (2011)

Protocolos

Effective analysis of passion flower by HPTLC fingerprinting, in conjunction with a comprehensive range of related reference materials, enables fast and efficient identification of this plant material.

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