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M2392

Supelco

Meprobamate

analytical standard

Sinônimo(s):

2-Methyl-2-propylpropane-1,3-diol dicarbamate, MPB

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About This Item

Fórmula empírica (Notação de Hill):
C9H18N2O4
Número CAS:
57-53-4
Peso molecular:
218.25
Número CE:
200-337-5
Número MDL:
MFCD00063428
Código UNSPSC:
41116107
ID de substância PubChem:
329817940
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

200

controle de medicamentos

USDEA Schedule IV; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

formato

neat

cadeia de caracteres SMILES

CCCC(C)(COC(N)=O)COC(N)=O

InChI

1S/C9H18N2O4/c1-3-4-9(2,5-14-7(10)12)6-15-8(11)13/h3-6H2,1-2H3,(H2,10,12)(H2,11,13)

chave InChI

NPPQSCRMBWNHMW-UHFFFAOYSA-N

Informações sobre genes

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

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Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ações bioquímicas/fisiológicas

Enhances GABAA receptor activity by increasing Cl− currents. At high concentrations, blocks NMDA glutamate receptor currents.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
126F0690
124F0648

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Visite a Biblioteca de Documentos

Arun Kumar et al.
Regulatory toxicology and pharmacology : RTP, 57(2-3), 146-156 (2010-02-16)
This study presents a step-wise development of a quantitative pharmaceutical risk assessment (QPhRA, hereafter) framework, including Monte Carlo uncertainty analysis for meprobamate, carbamazepine, and phenytoin during (1) accidental exposures of stream water and fish consumption and (2) direct ingestion of
Fabien Bévalot et al.
International journal of legal medicine, 125(3), 463-468 (2011-02-22)
The use of vitreous humor (VH) as an alternative matrix to blood in the field of forensic toxicology has been described for numerous drugs. Interpretation of drug concentrations measured in VH, as in other matrices, requires statistical analysis of a
Shane A Snyder et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 61(1), 145-154 (2010-01-09)
The presence of pharmaceuticals and endocrine disrupting compounds (EDCs) in the environment raises many questions about risk to the environment and risk to human health. Researchers have attributed adverse ecological effect effects to the presence of these compounds, particularly EDCs
Iain M McIntyre et al.
Journal of analytical toxicology, 36(3), 177-181 (2012-03-16)
Carisoprodol is a therapeutic and occasionally abused centrally acting muscle relaxant. We compare central blood and liver concentrations of carisoprodol and the metabolite meprobamate to concentrations in peripheral blood in 11 medical examiner cases. Specimens were initially screened for alcohol
Gudrun Høiseth et al.
European journal of clinical pharmacology, 68(11), 1561-1565 (2012-04-25)
Carisoprodol, a frequently used muscle relaxant, can cause potentially fatal intoxications. Conversion to its active metabolite meprobamate is almost solely mediated by cytochrome P450 2C19 (CYP2C19), and mutations in this enzyme could have significant effects on serum concentrations. The objective
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