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F8755

Supelco

Fenbufen

analytical standard

Sinônimo(s):

γ-Oxo-(1,1′-biphenyl)-4-butanoic acid

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About This Item

Fórmula linear:
C6H5C6H4CO(CH2)2CO2H
Número CAS:
36330-85-5
Peso molecular:
254.28
Número CE:
252-979-0
Número MDL:
MFCD00056701
Código UNSPSC:
41116107
ID de substância PubChem:
329799772
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

184-187 °C (lit.)

aplicação(ões)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Formato

neat

cadeia de caracteres SMILES

OC(=O)CCC(=O)c1ccc(cc1)-c2ccccc2

InChI

1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19)

chave InChI

ZPAKPRAICRBAOD-UHFFFAOYSA-N

Informações sobre genes

human ... MMP2(4313) , MMP3(4314) , MMP9(4318)

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Descrição geral

Fenbufen belongs to the class of non-steroidal anti-inflammatory drugs, widely used as an antipyretic and analgesic in medical applications. Its mode of action involves the inhibition of cyclooxygenase enzyme and thereby prevents the synthesis of certain prostaglandins.

Aplicação

Fenbufen may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H301

Declarações de precaução

P301 + P310

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificados de análise (COA)

Lot/Batch Number

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Bingxin Li et al.
International journal of pharmaceutics, 287(1-2), 89-95 (2004-11-16)
Layered double hydroxides (LDHs) or so-called anionic clays consist of cationic brucite-like layers and exchangeable interlayer anions. Because of their biocompatibility, these layered inorganic solids can be used as host materials to create drug-LDH host-guest supramolecular structures. Because of the
Ho-Lien Huang et al.
Biomaterials, 34(13), 3355-3365 (2013-02-07)
This study is concerned with the development of an agent for single photon emission computer tomography (SPECT) for imaging inflammation and tumor progression. [(123)I]Iodooctyl fenbufen amide ([(123)I]IOFA) was prepared from the precursor N-octyl-4-oxo-4-(4'-(trimethylstannyl)biphenyl-4-yl)butanamide with a radiochemical yield of 15%, specific
Z X Meng et al.
Colloids and surfaces. B, Biointerfaces, 84(1), 97-102 (2011-01-14)
Drug (Fenbufen, FBF)-loaded poly(D,L-lactide-co-glycolide) (PLGA) and PLGA/gelatin nanofibrous scaffolds were fabricated via electrospinning technique. The influences of gelatin content, fiber arrangement, crosslinking time and pH value of the buffer solution on FBF release behavior of the resulting nanofibrous scaffolds were
I Bratu et al.
Biopolymers, 77(6), 361-367 (2005-02-04)
1H-NMR spectra of aqueous solutions of fenbufen and two cyclodextrins (alpha- or gamma-cyclodextrin, respectively) mixtures confirm the formation of an inclusion complex if gamma-cyclodextrin is used, whereas in the case of alpha-cyclodextrin no inclusion complex was obtained. The stoichiometry of
Interstitial nephritis, toxic epidermal necrolysis and liver dysfunction associated to fenbufen.
N Krivoy et al.
Clinical rheumatology, 16(5), 489-490 (1997-11-05)
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