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Documentos Principais

C0465000

Carbimazole

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1-carboxylic acid ethyl ester

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About This Item

Fórmula empírica (Notação de Hill):
C7H10N2O2S
Número CAS:
22232-54-8
Peso molecular:
186.23
Código UNSPSC:
41116107
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

carbimazole

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

InChI

1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3

chave InChI

CFOYWRHIYXMDOT-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Carbimazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Adoree Yi Ying Lim et al.
Singapore medical journal, 54(7), e133-e136 (2013-08-01)
A 24-year-old Chinese woman with Graves' disease presented with myositis two months after treatment with carbimazole. The patient's myositis resolved with hydration and cessation of carbimazole. No other causes of myositis were found, and a change in the medication to
Matteo Cassina et al.
Birth defects research. Part A, Clinical and molecular teratology, 94(8), 612-619 (2012-04-19)
Clinical hyperthyroidism has been associated with an increased risk of maternal, fetal, and neonatal complications. The available antithyroid drugs are methimazole/carbimazole and propylthiouracil. Several case reports and some epidemiologic studies suggest that methimazole/carbimazole exposure during the first trimester of pregnancy
Kirsten Campbell et al.
Australian family physician, 41(8), 564-572 (2012-11-13)
Thyrotoxicosis is common in the Australian community and is frequently encountered in general practice. Graves disease, toxic multinodular goitre, toxic adenoma and thyroiditis account for most presentations of thyrotoxicosis. This article outlines the clinical presentation and evaluation of a patient
[59 year-old man with skin and eye alterations and diabetes mellitus].
N Ewald et al.
Deutsche medizinische Wochenschrift (1946), 137(19), 997-998 (2012-05-03)
Maternal thyrotoxicosis and fetal goitre requiring in utero therapy for hypothyroidism and subsequent neonatal therapy for hyperthyroidism.
Katie Groom et al.
Journal of paediatrics and child health, 49(1), E102-E103 (2013-01-17)
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