BP802

Lamivudine

British Pharmacopoeia (BP) Reference Standard

• Sinônimo(s): 2′,3′-Dideoxy-3′-thiacytidine, 3TC, Epivir, Epivir-HBV, Heptovir, Zeffix
• Fórmula empírica (Notação de Hill): C₈H₁₁N₃O₃S
• Número CAS: 134678-17-4
• Peso molecular: 229.26
• Número MDL: MFCD00869739
• Código UNSPSC: 12352200
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: lamivudine
• forma: solid
• prazo de validade: limited shelf life, expiry date on the label
• fabricante/nome comercial: BP
• aplicação(ões): pharmaceutical
• formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: NC1=NC(=O)N(C=C1)[C@@H]2CS[C@H](CO)O2
• InChI: 1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1
• chave InChI: JTEGQNOMFQHVDC-NKWVEPMBSA-N

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Lamivudine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Abacavir, Zidovudine and Lamivudine Tablets

Zidovudine and Lamivudine Tablets

Abacavir and Lamivudine Tablets

Lamivudine Tablets

Ações bioquímicas/fisiológicas

Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is an analogue of cytidine, and can inhibit both types (1 and 2) of HIV reverse transcriptase as well as the reverse transcriptase of hepatitis B. It needs to be phosphorylated to its triphosphate form before it is active. 3TC-triphosphate also inhibits cellular DNA polymerase.

Embalagem

Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Warning
• Frases de perigo: H361
• Declarações de precaução: P280
• Classificações de perigo: Repr. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable