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Ginkgolide B

analytical standard

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About This Item

Fórmula empírica (Notação de Hill):
C20H24O10
Número CAS:
15291-77-7
Peso molecular:
424.40
Beilstein:
4727611
Número MDL:
MFCD05662347
Código UNSPSC:
85151701
ID de substância PubChem:
329770404
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

Impurezas

≤10.0% water

aplicação(ões)

food and beverages

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34[C@H]5C[C@@H](C(C)(C)C)[C@@]36[C@@H](O)C(=O)O[C@H]6O[C@@]4(C(=O)O5)[C@@]12O

InChI

1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3/t6-,7+,8-,9+,10+,11+,15+,17+,18+,19-,20-/m1/s1

chave InChI

SQOJOAFXDQDRGF-MMQTXUMRSA-N

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Descrição geral

Ginkgolide B is a diterpenoid compound belonging to the group of ginkgolides, isolated from Ginkgo biloba leaves, exhibiting a wide spectrum of pharmacological properties and is used for the treatment of Alzheimer′s disease, cerebral insufficiency and memory loss.

Aplicação

Ginkgolide B may be used as an analytical reference standard for the quantification of the analyte in phytopharmaceutical formulations and Ginkgo biloba L. extract using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Outras notas

This compound is commonly found in plants of the genus: ginkgo

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
BCCG7839
BCCG4211
BCCC0216
BCBW8672
BCBR9461V

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Leonid B Krivdin
Progress in nuclear magnetic resonance spectroscopy, 108, 17-73 (2018-12-13)
Structural applications of theoretical calculations of carbon-hydrogen spin-spin coupling constants are reviewed covering papers published mainly during the last 10-15 years with a special emphasis on the most notable studies of hybridization, substitution and stereoelectronic effects together with the investigation of
Determination of ginkgolide A, B, and bilobalide in biloba L. extracts by microdialysis-HPLC
Chiu L-H, et al.
Analytical and Bioanalytical Chemistry, 379(3), 445-448 (2004)
Min Sun Choi et al.
Metabolites, 9(7) (2019-07-10)
Ginkgo leaf extract (GLE) is a popular herbal medicine and dietary supplement for the treatment of various diseases, including cardiovascular disease. GLE contains a variety of secondary plant metabolites, such as flavonoids and terpenoids, as active components. Some of these
Karyn M Maclennan et al.
Progress in neurobiology, 67(3), 235-257 (2002-08-10)
Ginkgo biloba extracts such as EGb-761 have been suggested to have a multitude of beneficial effects on CNS function, from enhancing cognitive function in dementia to facilitating recovery from acute forms of neural damage such as hypoxia/ischemia. Ginkgolide B, one
Xiao Chu et al.
Molecules (Basel, Switzerland), 16(9), 7634-7648 (2011-09-09)
Ginkgolide B is an anti-inflammatory extract of Ginkgo biloba and has been used therapeutically. It is a known inhibitor of platelet activating factor (PAF), which is important in the pathogenesis of asthma. Here, a non-infectious mouse model of asthma is
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