48912-U

ProClin^™ 300

pkg of 50 mL, ProClin^™ preservative for use in IVD manufacturing, CMIT/MIT 3 %

• Sinônimo(s): 3% solution of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-Methyl-4-isothiazolin-3-one
• Código UNSPSC: 12352201
• NACRES: NA.21

Propriedades

• Nível de qualidade: 300
• forma: liquid
• prazo de validade: 3 yr
• contém: Alkyl Carboxylate
• composição: CMIT/MIT, 3%
• embalagem: pkg of 50 mL
• Parâmetros: <45 °C operating temperature
• cor: colorless to light yellow
• matriz: Modified glycol
• operating pH range: 2.5-8.5
• pH: 4.1 (100 g/L)
• pb: 189 °C
• pf: -40 °C
• solubilidade: water: soluble
• densidade: 1.03 g/cm³

Descrição

Descrição geral

ProClin^™ preservatives are water-soluble preparations of biocides that are generally used to increase the shelf life of reagents. ProClin^™ 300 comprises of 3% of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and 2-methyl-4-isothiazloin-3-one (MIT) in a salt-free proprietary glycol containing an alkly carboxylate stabilizer. It has a recommended working pH range as 2.5 - 8.5.

Aplicação

For use in IVD Manufacturing

ProClin^™ 300 is suitable for preparation of different buffers like ELISA buffer, sample and substrate dilution buffers for Single-Molecule Arrays (Simoa assay) and Immunoenzymatic assay. Additionally, Proclin^™ may be used in preparing storage buffer to store beads coupled with coronavirus nucleocapsid protein for the serological multiplex assay.

ProClin^™ biocides preservatives are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin^™ toxicity prevent microorganisms from developing high levels of resistance, making ProClin^™ highly efficient even over extended storage periods of your IVD components.

Ações bioquímicas/fisiológicas

ProClin^™ products contain active substances like CMIT and MIT which inhibit the Krebs cycle at four different check points, the enzymes pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, and NADH dehydrogenase. The inhibition of Krebs cycle leads to effective broad-spectrum biocidal activity against bacteria, fungi, and yeast.

Informações legais

ProClin is a trademark of LANXESS Corp.

Exoneração de responsabilidade

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Informações de segurança

• Pictogramas: GHS05,GHS07,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H302 + H332,H314,H317,H410
• Declarações de precaução: P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
• Código de classe de armazenamento: 8A - Combustible corrosive hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 244.4 °F - closed cup
• Ponto de fulgor (°C): 118 °C - closed cup
• Equipamento de proteção individual: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter