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Tilmicosin

VETRANAL®, analytical standard, mix of isomers

Sinônimo(s):

20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin

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About This Item

Fórmula empírica (Notação de Hill):
C46H80N2O13
Peso molecular:
869.13
Número MDL:
MFCD19705582
Código UNSPSC:
41116107
ID de substância PubChem:
329754677
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

linha de produto

VETRANAL®

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

cadeia de caracteres SMILES

CC1OC(OCC(C(CC)O2)/C=C(/C=C/C(C(C)CC(CCN3CC(C)CC(C)C3)C(OC4OC(C)C(O)C(N(C)C)C4O)C(C)C(O)CC2=O)=O)C)C(OC)C(OC)C1O

InChI

1S/C46H80N2O13/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3/b15-14+,25-19+/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-/m1/s1

chave InChI

JTSDBFGMPLKDCD-XVFHVFLVSA-N

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Descrição geral

Tilmicosin is a semisynthetic macrolide antibiotic, with broad spectrum activity towards Mycoplasma spp., Pasteurella spp., and various gram-positive organisms in animals.

Aplicação

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tilmicosin may be used as a reference standard for the determination of the analyte in chicken, swine, cattle, sheep tissues and milk samples using liquid chromatography with ultraviolet detection (LC-UV).

Informações legais

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Palavra indicadora

Warning

Frases de perigo

H302,H373,H410

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Órgãos-alvo

Cardio-vascular system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
BCCG2736
BCCD7299
BCCB4507
BCBV4513
BCBT8086

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Sigma-Aldrich

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Sigma-Aldrich

T6134

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P Bosi et al.
Journal of animal science, 89(12), 4043-4053 (2011-07-05)
The aim of this study was to determine the effects of 3 antibiotics used for pulmonary pathologies added in the feed of weaned pigs on growth performance, commensal microbiota, and immune response. At weaning, a total of 72 pigs were
David G McClary et al.
Journal of the American Veterinary Medical Association, 239(1), 129-135 (2011-07-02)
To determine associations between in vitro minimum inhibitory concentrations (MICs) of tilmicosin against Mannheimia haemolytica and Pasteurella multocida and in vivo tilmicosin treatment outcome among calves with clinical signs of bovine respiratory disease (BRD). Observational, retrospective, cohort study. 976 feeder
Michael D Apley et al.
Foodborne pathogens and disease, 9(3), 272-279 (2012-02-14)
When considering the development of antimicrobial resistance in food animals, comparing gross use estimates of different antimicrobials is of little value due to differences in potencies, duration of activity, relative effect on target and commensal bacteria, and mechanisms of resistance.
F J Reynaldi et al.
Revista Argentina de microbiologia, 42(4), 279-283 (2011-01-14)
American Foulbrood (AFB) caused by the spore-forming bacterium Paenibacillus larvae is the most serious disease of bacterial origin affecting larvae and pupae of honeybees. Antibiotics are used in many countries for the control of AFB in high incidence areas, but
Yingyu Liu et al.
Microbial drug resistance (Larchmont, N.Y.), 18(6), 604-615 (2012-09-01)
The Haemophilus parasuis respiratory tract pathogen poses a severe threat to the swine industry despite available antimicrobial therapies. To gain a more detailed understanding of the molecular mechanisms underlying H. parasuis response to tilmicosin treatment, microarray technology was applied to
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