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02010595

Valerenic acid

primary reference standard

Sinônimo(s):

(2E)-3-[(4S,7R,7aR)-2,4,5,6,7,7a-Hexadydro-3,7-dimethyl- 1H-inden-4-yl]-2-methyl-2-propenoic acid

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About This Item

Fórmula empírica (Notação de Hill):
C15H22O2
Número CAS:
3569-10-6
Peso molecular:
234.33
Beilstein:
3138020
Número MDL:
MFCD00075694
Código UNSPSC:
85151701
ID de substância PubChem:
329747383
NACRES:
NA.24

grau

primary reference standard

prazo de validade

limited shelf life, expiry date on the label

fabricante/nome comercial

HWI

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

food and beverages

cadeia de caracteres SMILES

[H][C@]12CCC(C)=C1[C@@H](CC[C@H]2C)\C=C(/C)C(O)=O

InChI

1S/C15H22O2/c1-9-4-6-12(8-11(3)15(16)17)14-10(2)5-7-13(9)14/h8-9,12-13H,4-7H2,1-3H3,(H,16,17)/b11-8+/t9-,12+,13-/m1/s1

chave InChI

FEBNTWHYQKGEIQ-SUKRRCERSA-N

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Descrição geral

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Aplicação

Reference standard in the analysis of herbal medicinal products.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
HWI02798-1
HWI03424
HWI02798
HWI00962
HWI01875-1

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Dietmar Benke et al.
Neuropharmacology, 56(1), 174-181 (2008-07-08)
Valerian extracts have been used for centuries to alleviate restlessness and anxiety albeit with unknown mechanism of action in vivo. We now describe a specific binding site on GABA(A) receptors with nM affinity for valerenic acid and valerenol, common constituents
K Murphy et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 17(8-9), 674-678 (2010-01-01)
Valerian root (Valeriana officinalis) is a popular and widely available herbal supplement, primarily used to treat insomnia and anxiety. Until recently, its mechanism of action has remained unknown. Neurobiological research has begun to show that the herb, with its active
Mohamad Mirzaei et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(21), 1870-1874 (2011-06-07)
In the present work, the applicability of hollow fiber-based liquid phase microextraction (HF-LPME) was evaluated for the extraction and preconcentration of valerenic acid prior to its determination by reversed-phase HPLC/UV. The target drug was extracted from 5.0 mL of aqueous
S Khom et al.
Neuropharmacology, 53(1), 178-187 (2007-06-26)
Valerian is a commonly used herbal medicinal product for the treatment of anxiety and insomnia. Here we report the stimulation of chloride currents through GABA(A) receptors (I(GABA)) by valerenic acid (VA), a constituent of Valerian. To analyse the molecular basis
Winfried Neuhaus et al.
Planta medica, 74(11), 1338-1344 (2008-08-16)
The roots and rhizome of Valeriana officinalis L . s. l. are therapeutically used for their sedative and sleep-enhancing effects. Some of the active compounds found in commonly used extracts are the sesquiterpenic acids, especially valerenic acid, which was recently
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