MABF18

Anti-Interleukin-1 beta (IL-1B) Antibody, clone 4A7

clone AB34_41.4H12.4A7, from mouse

• Sinônimo(s): interleukin 1, beta, catabolin, pro-interleukin-1-beta, IL-1 beta, IL1-BETA, preinterleukin 1 beta, interleukin-1 beta, Catabolin
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• forma do anticorpo: purified antibody
• tipo de produto de anticorpo: primary antibodies
• clone: AB34_41.4H12.4A7, monoclonal
• reatividade de espécies: human
• técnica(s): western blot: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_000567
• nº de adesão UniProt: P01584
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... IL1B(3553)

Descrição

Descrição geral

Interleukin-1 (IL-1) is a cytokine that is thought to be connected to neurodegeneration and in central nervous system-mediated defense reactions to inflammation. Interleukin-1 beta (IL-1B) maintains mitogen-induced proliferation, IL-2 production and expression of IL-2R. IL-1 beta also seems to have the ability to boost the number of cells that move into the G1 phase of the cell cycle. IL-1 beta also has the capacity to stimulate apoptosis on normal human fetal membranes. IL-1 beta may play an important role in inflammation regulating cytokine networks.

Imunogênio

Full length recombinant protein corresponding to human Interleukin-1 beta.

Aplicação

Anti-Interleukin-1 beta (IL-1B) Antibody, clone 4A7 is an antibody against Interleukin-1 beta (IL-1B) for use in WB.

Luminex Assay Analysis: A previous lot was used by an independent laboratory in Luminex (Dr. Gerard Zurawski, Baylor Institute for Immunology Research, Dallas, TX).

Research Category
Inflammation & Immunology

Research Sub Category
Cytokines & Cytokine Receptors

Qualidade

Evaluated by Western Blot in lysate from cells expressing human Interleukin-1 beta recombinant protein.

Western Blot Analysis: 0.5 µg/mL of this antibody detected 10 µg of human Interleukin-1 beta recombinant protein.

Descrição-alvo

~17 kDa observed

Ligação

Replaces: 04-462; MABF22

forma física

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Nota de análise

Control
Human Interleukin-1 beta recombinant protein

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable