Pular para o conteúdo
Merck
Todas as fotos(1)

Key Documents

MAB3070

Sigma-Aldrich

Anti-Granzyme B Antibody, clone GrB-7

culture supernatant, clone GrB-7, Chemicon®

Sinônimo(s):

Anti-Anti-C11, Anti-Anti-CCPI, Anti-Anti-CGL-1, Anti-Anti-CGL1, Anti-Anti-CSP-B, Anti-Anti-CSPB, Anti-Anti-CTLA1, Anti-Anti-CTSGL1, Anti-Anti-HLP, Anti-Anti-SECT

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

100

forma do anticorpo

culture supernatant

tipo de produto de anticorpo

primary antibodies

clone

GrB-7, monoclonal

reatividade de espécies

human

fabricante/nome comercial

Chemicon®

técnica(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

Isotipo

IgG2a

nº de adesão NCBI

NM_004131.3

nº de adesão UniProt

P10144

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... GZMB(3002)

Especificidade

Monoclonal antibody recognizes the 33 kDa granzyme B.

Reacts specifically with human serine protease granzyme B. Does not cross-react with human granzyme A. Granzyme B localizes in cytoplasmic granules and can be used as a marker for NK cells and activated cytotoxic T-cells.

Aplicação

Detect Granzyme B using this Anti-Granzyme B Antibody, clone GrB-7 validated for use in WB, IH(P).
Immunoblotting

Immunohistochemistry of granzyme B-expressing lymphocytes in sublimate sections and formalin-fixed paraffin-embedded tissues (1:20 dilution). Does not react with other cell types. Cannot be used on frozen sections.

Note on the use of MAB3070 on paraffin sections:

Tissue slides should be pretreated with an antigen retrieval method, such as treatment with 0.1M sodium citrate for 10 min at 100°C. A working dilution of 1:20 is advised, but optimal working dilutions must be determined by end user.
Research Category
Apoptosis & Cancer

Metabolism
Research Sub Category
Apoptosis - Additional

Enzymes & Biochemistry

forma física

Liquid

Armazenamento e estabilidade

Maintain at -20°C for up to 12 months.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Não está encontrando o produto certo?  

Experimente o nosso Ferramenta de seleção de produtos.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

T F Barth et al.
Virchows Archiv : an international journal of pathology, 436(4), 357-364 (2000-06-02)
In contrast to primary gastric lymphomas of B-cell type, little is known about primary gastric T-cell lymphomas. We describe three cases with remarkably similar features: diffuse growth, epitheliotropism, medium too large cell size, high apoptotic rates, and a CD3+, CD4+
Milan Fiala et al.
Journal of neuroinflammation, 7, 76-76 (2010-11-11)
The contribution of inflammation to neurodegenerative diseases is increasingly recognized, but the role of inflammation in sporadic amyotrophic lateral sclerosis (sALS) is not well understood and no animal model is available. We used enzyme-linked immunosorbent assays (ELISAs) to measure the
Functional dissociation between proforms and mature forms of proteinase 3, azurocidin, and granzyme B in regulation of granulopoiesis.
Stefan Skold, Lennart Zeberg, Urban Gullberg, Tor Olofsson
Experimental Hematology null
Regulatory, effector, and cytotoxic T cell profiles in long-term kidney transplant patients.
Joanna Ashton-Chess,Emilie Dugast,Robert B Colvin,Magali Giral,Yohann Foucher,Anne Moreau et al.
Journal of the American Society of Nephrology null
P C de Bruin et al.
Blood, 84(11), 3785-3791 (1994-12-01)
T-cell non-Hodgkin's lymphomas can be considered the neoplastic equivalents of immunologically functional, site-restricted T lymphocytes. Little is known about the occurrence and clinical behavior of T-cell lymphomas that are the neoplastic equivalents of different functional T-cell subsets. Here, we investigated
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica