HCYTAAB-17K

MILLIPLEX^® Human Cytokine Autoantibody Panel

• NACRES: NA.47

Propriedades

• reatividade de espécies: human
• fabricante/nome comercial: Milliplex^®
• técnica(s): multiplexing: suitable
• método de detecção: fluorometric (Luminex^® xMAP^®)
• temperatura de armazenamento: 2-8°C

Descrição

Descrição geral

Anti-cytokine antibodies occur frequently and are present in healthy individuals and patients with acquired immunodeficiency and autoimmune diseases. Cytokines offering protection against microbes can be targeted by cytokine autoantibodies, leading to life-threatening infections. Some infections associated with anti-cytokine antibodies include M. tuberculosis, Salmonella, S. aureus. E. coli, Histoplasma, and more. The presence of cytokine autoantibodies in autoimmune disease can influence disease severity and activity. These autoimmune diseases may include systemic lupus erythematosus (SLE), multiple sclerosis (MS), Sjögren′s syndrome, rheumatoid arthritis (RA), and acute respiratory distress syndrome. Measuring cytokine autoantibodies may be useful for disease monitoring and efficacy of treatment.The MILLIPLEX^® MAP Human Cytokine Autoantibody Magnetic Bead Panel is a 15-plex kit to be used for the simultaneous detection and profiling of any or all of the following autoantibody analytes in serum and plasma samples: Anti-BAFF, Anti-G-CSF, Anti-IFNβ, Anti-IFNγ, Anti-IL-1α, Anti-IL-6, Anti-IL-8, Anti-IL-10, Anti-IL-12 (p40), Anti-IL-15, Anti-IL-17A, Anti-IL-17F, Anti-IL-18, Anti-IL-22, and Anti-TNFα. For this particular panel, 4 assay control beads are also included as part of the base kit format.

Aplicação

The Human Cytokine Autoantibody panel is a bead-based multiplex assay based on the Luminex^® xMAP technology which enables the simultaneous analysis of cytokine autoantibodies in human serum and plasma samples.This is assay yields results in Median Fluorescence Intensity (MFI).Four assay control beads are included in the base kit.This is an overnight or 2 hour incubation assay.This assay requires 25 μL of 1:100 diluted plasma or serum.Analytes available:BAFF/Blys;G-CSF;IFNβ;IFNγ;IL-1α;IL-6;IL-8;IL-10;IL-12 (p40);IL-15;IL-17A;IL-17F;IL-18;IL-22;TNFα

Características e benefícios

Design your multiplex kit by choosing available analytes within this panel.

Embalagem

96-well plate

Armazenamento e estabilidade

Recommended storage for kit components is 2 - 8°C.

Informações legais

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Pictogramas: GHS07,GHS09
• Palavra indicadora: Warning
• Frases de perigo: H317,H319,H411
• Declarações de precaução: P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable