FCMAB291F

Milli-Mark^®Anti-Cytokeratin 5 Antibody, 6-FITC, clone D5/16B4

clone D5/16B4, Milli-Mark^®, from mouse

• Sinônimo(s): 58 kDa cytokeratin, epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types, keratin 5, keratin 5 (epidermolysis bullosa simplex,Dowling-Meara/Kobner/Weber-Cockayne types), keratin, type II cytoskeletal 5
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: FITC conjugate
• forma do anticorpo: purified antibody
• tipo de produto de anticorpo: primary antibodies
• clone: D5/16B4, monoclonal
• reatividade de espécies: human
• fabricante/nome comercial: Milli-Mark^®
• técnica(s): flow cytometry: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_000415.2
• nº de adesão UniProt: P13647
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... KRT5(3852)

Descrição

Descrição geral

The cytokeratins are a family of intermediate filaments found in almost all epithelial cells. They are divided into four subclasses depending on their patterns of reactivity and electrophoretic characteristics and are also arranged I a numbered series of 20 or more acoring to molecular weight and isoelectric point (Quinlan et al. 1985). Types 5 and 6 of cytokeratin (CK5/6) are in high frequency in mesothelial cells, as opposed to cells of adenocarcinoma. CK5/6 has been shown to be a reliable marker for mesothelioma and squamous cell carcinoma of the lung and Bowen′s disease. It does not react with pulmonary adenocarcinoma.

Especificidade

Antibody recognizes Human Cytokeratin.

Imunogênio

Purified cytokeratin 5 (Wild, 1986) (Mischke, 1987).

Aplicação

Milli-MarkAnti-Cytokeratin 5 Antibody, 6-FITC, clone D5/16B4 is an antibody against Cytokeratin 5 for use in FC.

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

Qualidade

Evaluated by flow cytometry using A431 cells

Descrição-alvo

The calculated for Cytokeratin is 62 kDa, however, different isoforms state Cytokeratin 4 (59 kDa), Cytokeratin 5 (58 kDa) and Cytokeratin 6 (56 kDa).

forma física

Protein A purified

Purified mouse monoclonal IgG1 conjugated to FITC in PBS buffer with 15mg/mL BSA and sodium azide at 0.1%.

Armazenamento e estabilidade

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

Nota de análise

Control
A431 cells

Informações legais

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable