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Key Documents

ECM642

Sigma-Aldrich

In Vitro Vascular Permeability Assay (96-well)

This In Vitro Vascular Permeability Assay kit employs a 96-well plate, and provides an efficient system for evaluating the effects of chemicals & drug compounds on endothelial cell adsorption, transport & permeability.

Sinônimo(s):

Endothelial cell model for permeability assay

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About This Item

Código UNSPSC:
12352207
eCl@ss:
32161000
NACRES:
NA.32

Nível de qualidade

reatividade da espécie (prevista por homologia)

all

fabricante/nome comercial

Chemicon®

técnica(s)

cell based assay: suitable

método de detecção

fluorometric

Condições de expedição

wet ice

Aplicação

Research Category
Cell Structure
The Millipore® In Vitro Vascular Permeability Assay kit provides an efficient system for evaluating the effects of chemicals and drug compounds on endothelial cell adsorption, transport, and permeability. It is ideal for measuring compounds that may disrupt or protect an endothelial monolayer. Each In Vitro Vascular Permeability Assay Kit contains sufficient reagents for the evaluation of 96 samples. The In Vitro Vascular Permeability Assay Kit is intended for research use only, not for diagnostic or therapeutic applications.

Componentes

96-Well Permeability Insert Assembly, Collagen-coated: One 96-well receiver tray containing 96 connected porous cell culture inserts pre-coated with type I rat-tail collagen.

Receiver Tray, 96-Well: Two 96-well plates.

FITC-Dextran Solution: Two vials containing 250 µL.

Cell Stain: One bottle containing 10 mL.

Black Plate, 96-Well Opaque: One 96-well plate.

Armazenamento e estabilidade

Store kit materials at 2-8°C; use within 4 months from date of receipt. Do not freeze.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Millipore is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

10-13 - German Storage Class 10 to 13

Classe de risco de água (WGK)

WGK 2


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Peng Sun et al.
The Journal of pharmacology and experimental therapeutics, 382(3), 266-276 (2022-07-03)
Diabetic nephropathy is a leading cause of end-stage renal disease, characterized by endothelial dysfunction and a compromised glomerular permeability barrier. Dysregulation of the angiopoietin 1 (ANGPT1)/angiopoietin 2 (ANGPT2) signaling axis is implicated in disease progression. We recently described the discovery
Mohammad Shoeb et al.
Environmental research, 180, 108900-108900 (2019-11-13)
Inhalation of welding fume (WF) can result in the deposition of toxic metals, such as manganese (Mn), in the brain and may cause neurological changes in exposed workers. Alterations in telomere length are indicative of cellular aging and, possibly, neurodegeneration.

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