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Documentos Principais

CBL561

Sigma-Aldrich

Anti-CD24 Antibody, clone SN3

clone SN3, Chemicon®, from mouse

Sinônimo(s):

Heat Stable Antigen, HAS

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

forma do anticorpo

affinity purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

SN3, monoclonal

reatividade de espécies

human

fabricante/nome comercial

Chemicon®

técnica(s)

flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotipo

IgG1

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

Especificidade

The antibody reacts with the CD24 antigen a heavily glycosylated molecule that migrates as a broad band of 35-45 kDa on both reducing and non-reducing SDS gel electrophoresis. CD24 is attached to the cell membrane via a glycosyl phosphatidylinositol (GPI) anchor and is expressed at multiple stages of B cell development, beginning with the bone marrow CD34 positive pro-B cell compartment and continuing through mature surface IgM positive/IgD positive B cells. CD24 is also expressed on the vast majority of B-lineage acute lymphoblastic leukaemias, B cell chronic lymphocytic leukaemias and B cell non-Hodgkin′s lymphoma. In the normal spleen, mantle zone lymphocytes are CD24 strongly positive, but germinal center cells are CD24 negative or CD24 weakly positive.

Imunogênio

Glycoproteins purified from human NALM-1 cell line.

Aplicação

Anti-CD24 Antibody, clone SN3 detects level of CD24 & has been published & validated for use in FC, IP, IH.
Immunocytochemistry on frozen tissue sections.

Flow Cytometry: 1:50 - 1:100 per 10e6 cells in 100 μL final volume.

Optimal working dilutions must be determined by the end user.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology

forma física

Affinity purified immunoglobulin by Protein G chromatography. Liquid in 1 mL of PBS, pH 7.4 containing no preservatives.
Format: Purified

Armazenamento e estabilidade

Maintain at -20°C for up to 12 months from date of receipt in undiluted aliquots.

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Chronic lymphocytic leukemia progenitor cells carry the antigens T65, BA-1, and Ia.
Perri, R T, et al.
Blood, 61, 871-875 (1983)
Follicular mantle zone cell subpopulations detected by monoclonal antibody SN3.
Barcos, M, et al.
Hematological Oncology, 4, 251-259 null
Clinical usefulness of monoclonal-antibody phenotyping in childhood acute lymphoblastic leukemia.
Kersey, J, et al.
Lancet, 2, 1419-1423 (1982)
New monoclonal antibodies SN3, SN3a, and SN3b directed to sialic acid of glycoprotein on human non-T leukemia cells.
Fukukawa, T, et al.
Experimental Hematology, 14, 850-855 (1986)
The human fetal omentum: a site of B cell generation.
Solvason, N and Kearney, J F
The Journal of Experimental Medicine, 175, 397-404 (1992)

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