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Merck
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Documentos Principais

AB1583

Sigma-Aldrich

Anti-Neuropeptide Y Antibody

serum, Chemicon®

Sinônimo(s):

NPY

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

sheep

Nível de qualidade

forma do anticorpo

serum

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

reatividade de espécies

invertebrates, rabbit, guinea pig

fabricante/nome comercial

Chemicon®

técnica(s)

immunohistochemistry: suitable
radioimmunoassay: suitable

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

rabbit ... Npy(100301542)

Especificidade

Neuropeptide Y (NPY). The specificity was determined by RIA. Synthetic peptides somatostatin-14, leu-enkephalin, met-enkephalin, oxytocin, Agr8-vasopressin, vasoactive intestinal peptide and angiotensin II showed less than 0.005% cross reactivity and substance P less than 0.02%. Peptide YY and bovine pancreatic polypeptide showed approximately 36% and 0.05% cross reactivity respectively. Human Peptide YY shares 65% homology amino acid sequence for human NPY.



Synthetic NPY completely abolishes radio labeled NPY binding to NPY antibody in RIA and antibody binding to tissue antigen.

Imunogênio

Synthetic NPY peptide conjugated to bovine thyroglobulin.

Aplicação

Detect Neuropeptide Y using this Anti-Neuropeptide Y Antibody validated for use in IH, RIA.
Immunohistochemistry: 1:5,000 on rabbit and guinea pig using an ABC detection method.

RIA

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism

Hormones & Receptors

forma física

Sheep serum. Lyophilized, no preservatives. Reconstitute with 100 μL of sterile distilled water.

Armazenamento e estabilidade

Maintain at -20 to -70°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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J A Evans et al.
Neuroscience, 202, 300-308 (2011-12-14)
In mammals, light entrains the central pacemaker within the suprachiasmatic nucleus (SCN) through both a direct neuronal projection from the retina and an indirect projection from the intergeniculate leaflet (IGL) of the thalamus. Although light comparable in intensity to moonlight
Quantitative study of NPY-expressing GABAergic neurons and axons in rat spinal dorsal horn.
Polgar E, Sardella TC, Watanabe M, Todd AJ
The Journal of Comparative Neurology null
Darren Cameron et al.
Pain, 156(10), 2061-2071 (2015-06-24)
The anterolateral tract (ALT), which originates from neurons in lamina I and the deep dorsal horn, represents a major ascending output through which nociceptive information is transmitted to brain areas involved in pain perception. Although there is detailed quantitative information
Alexander V Loktev et al.
Cell reports, 5(5), 1316-1329 (2013-12-10)
Human monogenic obesity syndromes, including Bardet-Biedl syndrome (BBS), implicate neuronal primary cilia in regulation of energy homeostasis. Cilia in hypothalamic neurons have been hypothesized to sense and regulate systemic energy status, but the molecular mechanism of this signaling remains unknown.
The relationship of the birth date of rat sympathetic neurons to the target they innervate.
Chubb DP, Anderson CR
Developmental Dynamics null

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