8.55051

Biotin NovaTag^® resin

Novabiochem^®

• Sinônimo(s): N-Biotin-NÆ-Fmoc-ethylenediamine MPB-AM resin
• Código UNSPSC: 12352209

Propriedades

• linha de produto: NovaSyn^® TG; Novabiochem^®
• forma: beads
• adequação da reação: reaction type: Fmoc solid-phase peptide synthesis
• fabricante/nome comercial: Novabiochem^®
• aplicação(ões): peptide synthesis
• grupo funcional: amine
• temperatura de armazenamento: 15-25°C

Descrição

Descrição geral

Biotin NovaTag resin is an ideal tool for the synthesis of peptides labeled with biotin. As the biotin moiety is incorporated into the linker, its use eliminates the problems associated with biotin-labeling of peptides, namely poor solubility and sluggish coupling kinetics of biotin and its derivatives. Following peptide assembly under standard Fmoc SPPS conditions, cleavage with TFA affords the peptide labeled with biotin. For a recent applications see ^[1,2].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

^[1] M. Carraz, et al. (2009) Chemistry & Biology, 16, 702.
^[2] S. Millward, et al. (2007) Chem. Biol., 2, 625.

Ligação

Replaces: 04-12-3901

Nota de análise

Color (visual): white to light yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.35 - 0.65 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer metrix is copoly (styrene - 1% DVB), 100 - 200 mesh.

Informações legais

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany

NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable