5310-OP

HEPES

>= 99%, Free Acid, fine powder, OmniPur^® Grade

• Sinônimo(s): Ácido 4-(2-hidroxietil)piperazina-1-etanossulfônico, Ácido N-(2-hidroxietil)piperazina-N′-2-etanossulfônico
• Fórmula empírica (Notação de Hill): C₈H₁₈N₂O₄S
• Número CAS: 7365-45-9
• Peso molecular: 238.30
• Beilstein: 883043
• Número MDL: MFCD00006158
• Código UNSPSC: 12352207
• NACRES: NA.21

Propriedades

• product name: HEPES, OmniPur^® Grade, >= 99%, Free Acid
• Nível de qualidade: 100
• forma: fine powder
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze
• cor: white
• faixa de pH útil: 6.8-8.2
• pKa (25 °C): 7.5
• Condições de expedição: ambient
• temperatura de armazenamento: 10-30°C
• cadeia de caracteres SMILES: OCCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)
• chave InChI: JKMHFZQWWAIEOD-UHFFFAOYSA-N

Descrição

Descrição geral

Molecular Biology grade

A₂₆₀ (0.1 M, water): ≤0.05 AU
A₂₈₀ (0.1 M, water): ≤0.05 AU
Assay (dried basis): ≥99
DNase: None detected
Heavy metals (as Pb): ≤0.001%
Phosphatase: None detected
pKa at 25°C: 6.80-8.20
Protease: None detected
RNase: None detected





Intended for laboratory and manufacturing use only. Not for drug, food, or household use.

Aplicação

<ul>
<li><strong>Phenothiazine appended thiophene derivative: a trilateral approach to copper ion detection in living cells and aqueous samples.</strong>: This study explores the use of HEPES buffer in the detection of copper ions, showcasing its utility in maintaining the stability of the sensor in aqueous solutions and live cell environments. The findings indicate that HEPES buffer plays a crucial role in the accuracy and efficiency of ion detection assays, which is essential for biochemists working with metal ion sensors (Ilakiyalakshmi et al., 2024).</li>
<li><strong>Evaluation of acute intravenous toxicity of HEPES: Is Good′s buffer good and safe enough for clinical utilization in nuclear medicine </strong>: This research assesses the safety of HEPES buffer for intravenous use, specifically its acute toxicity. The results are vital for biochemists in nuclear medicine, indicating that HEPES is a safe and effective buffering agent for clinical applications (Guleria et al., 2024).</li>
<li><strong>Nanoscale engineering of gold nanostars for enhanced photoacoustic imaging.</strong>: The study highlights the use of HEPES buffer in the synthesis of gold nanostars, which significantly improves photoacoustic imaging. This demonstrates the buffer′s importance in nanobiotechnology, particularly in enhancing the stability and functionality of nanomaterials used in imaging techniques (Zhang et al., 2024).</li>
<li><strong>Influx of zwitterionic buffer after intracytoplasmic sperm injection (ICSI) membrane piercing alters the transcriptome of human oocytes.</strong>: This article discusses how HEPES buffer influences the transcriptome of human oocytes post-ICSI, highlighting its role in reproductive biology and assisted reproductive technologies. The findings are crucial for biochemists focusing on fertility treatments and genetic studies (Mendola et al., 2024).</li>
<li><strong>One Method to Label Them All": A Single Fully Automated Protocol for GMP-Compliant 68Ga Radiolabeling of PSMA-11, Transposable to PSMA-I and PSMA-617.</strong>: This paper outlines a protocol using HEPES buffer for radiolabeling in nuclear medicine, emphasizing its application in producing radiopharmaceuticals. The research supports the buffer′s critical role in maintaining the quality and compliance of radiolabeling processes (Fouillet et al., 2024).</li>
</ul>

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable