341492

FeTPPS

A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro.

• Sinônimo(s): FeTPPS, 5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrinato Iron (III), Chloride
• Fórmula empírica (Notação de Hill): C₄₄H₂₈ClFeN₄O₁₂S₄
• Peso molecular: 1024.27
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥95% (TLC)
• forma: solid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; desiccated (hygroscopic); protect from light
• cor: dark brown
• solubilidade: water: soluble
• Condições de expedição: ambient
• temperatura de armazenamento: 2-8°C

Descrição

Descrição geral

A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Hence, serves as a selective peroxynitrite scavenger and decomposition catalyst. Provides cytoprotection against peroxynitrite (EC₅₀ = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.

A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Provides cytoprotection against peroxynitrite (EC₅₀ = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity.

Ações bioquímicas/fisiológicas

Cell permeable: no

EC50 = 5 µM for cytoprotection against peroxynitrite

Primary Target
Selective peroxynitrite scavenger

Product does not compete with ATP.

Reversible: no

Embalagem

Packaged under inert gas

Advertência

Toxicity: Standard Handling (A)

Reconstituição

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C.

Outras notas

Imam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci.914, 157.
Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable