317505

1,2-Dioctanoyl-sn-glycerol

Cell-permeable activator of protein kinase C (PKC).

• Sinônimo(s): 1,2-Dioctanoyl-sn-glycerol, DOG, PKC Activator IV
• Fórmula empírica (Notação de Hill): C₁₉H₃₆O₅
• Número CAS: 60514-48-9
• Peso molecular: 344.49
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• forma: oil
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze
• cor: clear colorless
• solubilidade: chloroform: soluble; ethyl acetate: soluble
• Condições de expedição: wet ice
• temperatura de armazenamento: −70°C
• InChI: 1S/C19H36O5/c1-3-5-7-9-11-13-18(21)23-16-17(15-20)24-19(22)14-12-10-8-6-4-2/h17,20H,3-16H2,1-2H3/t17-/m0/s1
• chave InChI: ZQBULZYTDGUSSK-KRWDZBQOSA-N

Descrição

Descrição geral

Cell-permeable activator of protein kinase C (PKC). Exhibits lower affinity for PKC_α than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.

Cell-permeable activator of protein kinase C; however, it has lower affinity for PKCa than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.

Ações bioquímicas/fisiológicas

Cell permeable: yes

Primary Target
Protein kinase C

Reversible: no

Embalagem

Packaged under inert gas

Advertência

Toxicity: Standard Handling (A)

Reconstituição

Unstable in solution; reconstitute just prior to use.

Nota de análise

Single spot by TLC

Outras notas

Ferro, T.J., et al. 1993. Am. J. Physiol. 264, L7.
MacEwan, D.J., et al. 1993. Eur. J. Pharmacol. 246, 9.
Davis, R.J. 1985. J. Biol. Chem.260, 1562.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable