204870-M

Complement C3d, Human

Complement C3d, Human is a native, 30 kDa polypeptide formed by the limited digestion of iC3b by trypsin or elastin. The binding of C3d to CR2 on B lymphocytes enhances B cell activation.

• Sinônimo(s): Complement Protein
• Código UNSPSC: 12352202

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥85% (SDS-PAGE)
• Formulário: liquid
• não contém: preservative
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; avoid repeated freeze/thaw cycles
• Impurezas: IgG, IgM, IgA, C5, Factor H, Factor I, trace
• temperatura de armazenamento: −70°C

Descrição

Descrição geral

Native, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30 kDa. The binding of C3d to CR2 (CD21) receptors present on B lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.

Native, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30,000. The binding of C3d to CR2 (CD21) receptors present on B-lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.

Advertência

Toxicity: Standard Handling (A)

forma física

In PBS, pH 7.2.

Nota de preparo

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstituição

Following initial thaw, aliquot and freeze (-20°C).

Outras notas

Luxembourg, A.T. and Cooper, N.R. 1994. J. Immunol.153, 4448.
Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA82, 4235.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable