07-841

Anti-phospho-IR/IGF1R (Tyr1158/Tyr1162/Tyr1163) Antibody

Upstate^®, from rabbit

• Sinônimo(s): CD220, Insulin Receptor / CD221, Insulin-like Growth Factor 1 Receptor
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• purificado por: affinity chromatography
• reatividade de espécies: mouse, human
• fabricante/nome comercial: Upstate^®
• técnica(s): western blot: suitable
• Isotipo: IgG
• nº de adesão NCBI: NM_000208.2; NM_001079817.1
• nº de adesão UniProt: P06213
• Condições de expedição: dry ice
• modificação pós-traducional do alvo: phosphorylation (pTyr1158/pTyr1162/pTyr1163)
• Informações sobre genes: human ... INSR(3643)

Descrição

Especificidade

Human and mouse phospho-Insulin Receptor (IR) Tyrosine 1158/1162/1163 and Insulin-like Growth Factor 1 Receptor (IGF1R) Tyr 1131/1135/1136. Rat reactivity is expected based on 100% sequence homology.

Predicted to cross-react with rat based on 100% sequence homology, but have not been tested.

Imunogênio

Peptide corresponding to the amino acid region encompassing the human, mouse, and rat phospho-Insulin Receptor (IR) Tyrosine 1158, 1162, and 1163 and Insulin-like Growth Factor 1 Receptor (IGF1R) Tyr 1131, 1135, and 1136.

Aplicação

Anti-phospho-IR/IGF1R (Tyr1158/Tyr1162/Tyr1163) Antibody detects level of phospho-IR/IGF1R (Tyr1158/Tyr1162/Tyr1163) & has been published & validated for use in WB.

Immunoblot Analysis: 1:1000 dilutions of this lot detected phospho-IR (Tyr1158/Tyr1162/Tyr1163) in RIPA lysate of untreated and insulin treated CHO cells transfected with IR.

Research Category
Signaling

Research Sub Category
Insulin/Energy Signaling

Qualidade

Routinely evaluated by immunoblot.

Descrição-alvo

155 kDa

forma física

100 μL of affinity purified rabbit polyclonal IgG in 50% storage buffer (PBS (without Mg²⁺ and Ca²⁺), pH 7.3 containing 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide) and 50% glycerol.

Affinity purified

Armazenamento e estabilidade

Stable for 2 years at -20°C from date of shipment.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerolcontaining solutions to become frozen during storage.

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable