07-692
Anti-Sar1 Antibody
Upstate®, from rabbit
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
Produtos recomendados
fonte biológica
rabbit
forma do anticorpo
purified antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
reatividade de espécies
monkey, mouse, rat, human
fabricante/nome comercial
Upstate®
técnica(s)
western blot: suitable
Isotipo
IgG
nº de adesão NCBI
Condições de expedição
wet ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... ROR1(4919)
Especificidade
Sar1
Imunogênio
KLH-conjugated, synthetic peptide corresponding to amino acids 46-62 (CKDDRLGQHVPTLHPTSE) of human Sar1 (a and b isoforms), with an N-terminal cysteine added for conjugation purposes
Aplicação
Detect Sar1 using this Anti-Sar1 Antibody validated for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
G-proteins
Kinases & Phosphatases
G-proteins
Kinases & Phosphatases
Qualidade
routinely evaluated by immunoblot on RIPA lysates from 3T3/A31 cells
Descrição-alvo
Mr 21kDa
forma física
Format: Purified
Protein A purified
Armazenamento e estabilidade
stable 2 years at -20°C from date of shipment
Nota de análise
Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
Informações legais
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Bethan Jones et al.
Nature genetics, 34(1), 29-31 (2003-04-15)
Dietary fat is an important source of nutrition. Here we identify eight mutations in SARA2 that are associated with three severe disorders of fat malabsorption. The Sar1 family of proteins initiates the intracellular transport of proteins in COPII (coat protein)-coated
A structural view of the COPII vesicle coat.
Bickford, Lincoln C, et al.
Current Opinion in Structural Biology, 14, 147-153 (2004)
Xue-Hai Liang et al.
Nucleic acids research, 46(19), 10225-10245 (2018-09-22)
RNase H1-dependent, phosphorothioate-modified antisense oligonucleotides (PS-ASOs) can enter cells through endocytic pathways and need to be released from the membrane-enclosed organelles, a limiting step for antisense activity. Accumulating evidence has suggested that productive PS-ASO release mainly occurs from late endosomes
The intracellular transport of chylomicrons requires the small GTPase, Sar1b.
Shoulders, Carol C, et al.
Current Opinion in Lipidology, 15, 191-197 (2004)
François-Xavier Campbell-Valois et al.
Molecular & cellular proteomics : MCP, 11(7), M111-M111 (2012-03-20)
Phagosomes, by killing and degrading pathogens for antigen presentation, are organelles implicated in key aspects of innate and adaptive immunity. Although it has been well established that phagosomes consist of membranes from the plasma membrane, endosomes, and lysosomes, the notion
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