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Merck
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Documentos Principais

06-903

Sigma-Aldrich

Anti-PKA Antibody, NT

Upstate®, from rabbit

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

forma do anticorpo

purified antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

reatividade de espécies

hamster, bovine, rat, pig, mouse, human

fabricante/nome comercial

Upstate®

técnica(s)

western blot: suitable

Isotipo

IgG

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... TYRO3(7301)

Especificidade

PKA, and recombinant human alpha isoform of PKA

Imunogênio

peptide (KKGSEQESVKEFLAK-C) based upon amino acids 8-22 of the human 41kDa alpha isoform of the catalytic subunit of PKA

Aplicação

Anti-PKA Antibody, NT detects level of PKA & has been published & validated for use in WB.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

Qualidade

routinely evaluated by immunoblot on rat brain microsomal preparation or PC-12 RIPA cell lysates

Descrição-alvo

41kDa

forma física

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol added to 30%
Format: Purified
Protein A chromatography

Armazenamento e estabilidade

2 years at -20°C

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1


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Ho-Lin Chuang et al.
Environmental toxicology, 36(9), 1873-1879 (2021-06-06)
Epimedium, is used traditionally in Chinese medicine to treat infertility problems. In this study, we establish the cell model to elucidate the protective effect of epimedium against ES by analyzing the molecular relationship between mitochondrial dynamics and steroidogenesis and to
Zhaoqing Zheng et al.
Journal of neurophysiology, 101(5), 2539-2549 (2009-03-06)
The cyclic AMP-dependent protein kinase (PKA) signaling pathway has been shown to be important in mechanisms of synaptic plasticity, although its direct and downstream signaling effects are not well understood. Using an in vitro model of eyeblink classical conditioning, we
Gregory Segala et al.
Nature communications, 10(1), 1833-1833 (2019-04-25)
In response to extracellular signals, many signalling proteins associated with the plasma membrane are sorted into endosomes. This involves endosomal fusion, which depends on the complexes HOPS and CORVET. Whether and how their subunits themselves modulate signal transduction is unknown.
Wanxu Guo et al.
Biology open, 10(5) (2020-10-14)
Podocytes are the major target in proteinuric kidney diseases such as diabetic nephropathy. The underlying molecular mechanisms by which high glucose (HG) results in podocyte damage remain unclear. This study investigated the regulatory role of Smad3, ezrin, and protein kinase
Fengjiao Sun et al.
International journal of molecular medicine, 41(5), 2493-2504 (2018-02-03)
Right ventricular (RV) remodeling coupled with extensive apoptosis in response to unrestrained biomechanical stress may lead to RV failure (RVF), which is the immediate cause of death in the majority of patients with pulmonary arterial hypertension (PAH). Overexpression of β2‑adrenergic

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