H-047

Hydrocodone-D₆ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (Notação de Hill): C₁₈H₁₅NO₃D₆
• Número CAS: 1007844-38-3
• Peso molecular: 305.40
• Número CE: 200-659-6
• Número MDL: MFCD01861538
• Código UNSPSC: 41116107
• ID de substância PubChem: 329815117
• NACRES: NA.24

Propriedades

• grau: certified reference material
• forma: liquid
• Características: Snap-N-Spike^®/Snap-N-Shoot^®
• embalagem: ampule of 1 mL
• fabricante/nome comercial: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• concentração: 100 μg/mL in methanol
• técnica(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicação(ões): forensics and toxicology
• formato: single component solution
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [2H]C([2H])([2H])Oc1ccc2C[C@@H]3[C@@H]4CCC(=O)[C@@H]5Oc1c2[C@]45CCN3C([2H])([2H])[2H]
• InChI: 1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1/i1D3,2D3
• chave InChI: LLPOLZWFYMWNKH-CWCHNPBGSA-N

Descrição

Descrição geral

This certified Snap-N-Spike^® solution is suitable for quantitation of hydrocodone levels or isotope dilution methods by LC/MS or GC/MS for pain prescription monitoring, clinical toxicology, pharmaceutical research, or forensic analysis. Hydrocodone is an opiate drug used as an analgesic to treat pain and as an antitussive for coughing or related conditions. Also known as dihydrocodeinone, it is one of the most common recreationally-abused prescription drugs due to its widespread availability. Common street names include “hydros”, “dones”, “vics”, and “itchies”.

Aplicação

• Quantitative plasma analysis for opiates: A robust gas chromatography-triple quadrupole mass spectrometry assay was developed for quantifying opiates in human blood samples, including hydrocodone. Hydrocodone-D₆ was utilized as an internal standard, enhancing the accuracy and reliability of drug monitoring in clinical toxicology (Saad et al., 2019).


• Advanced LC-MS/MS method for opioid analysis: A liquid chromatography-tandem mass spectrometry method was validated for the analysis of hydrocoDoneand its metabolites in human plasma. Hydrocodone-D₆ served as a critical internal standard, facilitating precise quantification and pharmacokinetic studies in pharmaceutical research (Valtier et al., 2013).

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS02,GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H225,H301 + H311 + H331,H370
• Declarações de precaução: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Órgãos-alvo: Eyes
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 49.5 °F - closed cup
• Ponto de fulgor (°C): 9.7 °C - closed cup