A-002

(±)-Amphetamine-d₅ (deuterium label on ring) solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (Notação de Hill): C₉D₅H₈N
• Número CAS: 65538-33-2
• Peso molecular: 140.24
• Número CE: 200-659-6
• Número MDL: MFCD00673255
• Código UNSPSC: 41116107
• ID de substância PubChem: 329770563
• NACRES: NA.24

Propriedades

• grau: certified reference material
• Nível de qualidade: 300
• forma: liquid
• Características: SNAP-N-SPIKE^®. SNAP-N-SHOOT^®
• embalagem: ampule of 1 mL
• fabricante/nome comercial: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
• concentração: 100 μg/mL in methanol
• técnica(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicação(ões): forensics and toxicology
• formato: single component solution
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CC(N)CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H]
• InChI: 1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/i2D,3D,4D,5D,6D
• chave InChI: KWTSXDURSIMDCE-VIQYUKPQSA-N

Descrição

Descrição geral

Amphetamine, a central nervous system stimulant, belongs to the phenethylamine clas. It is found in ADHD-treatment drugs such as Adderall^®, Vyvanse^®, and ProCentra^®. It is also used for the treatment of narcolepsy. Because of its stimulant effect, amphetamine is used recreationally as a performance-enhancer and illicit drug. This stable-labeled internal standard is suitable for quantitation of amphetamine levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or sports testing.

Aplicação

• Amphetamine-d5 solution as a mass spectrometry internal standard: The deuterium-labeled amphetamine (amphetamine-d5) serves as a precise internal standard for mass spectrometry, enhancing the accuracy of quantitative analyses in forensic toxicology and pharmaceutical testing. This application is crucial for identifying and quantifying amphetamine in biological samples, as demonstrated in a method developed for detecting psychoactive drugs (Barone et al., 2023).


• Stable isotope-labeled amphetamine for pharmaceutical research: Amphetamine-d5 is employed in pharmaceutical research to investigate the metabolic pathways of amphetamines. Its stable isotopic label allows for the tracking of amphetamine metabolites in complex biological matrices, offering insights into drug metabolism and pharmacokinetics (Alhazmi et al., 2020).


• Deuterated amphetamine in analytical chemistry: As a high-purity analytical reference material, amphetamine-d5 is used to calibrate and validate chromatographic and mass spectrometric methods. This ensures the reliability and reproducibility of analytical assays in both clinical and forensic settings, critical for drug monitoring and therapeutic drug management (Mohamed et al., 2016).

Informações legais

Adderall is a registered trademark of Richwood Pharmaceutical Company, Inc.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

ProCentra is a registered trademark of Outlook Pharmaceuticals, Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Vyvanse is a registered trademark of Shire, LLC

Informações de segurança

• Pictogramas: GHS02,GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H225,H301 + H311 + H331,H370
• Declarações de precaução: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Órgãos-alvo: Eyes
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 49.5 °F - closed cup
• Ponto de fulgor (°C): 9.7 °C - closed cup