860842P

18:0(2R-OH) Sulfo GalCer

Avanti Research^™ - A Croda Brand 860842P, powder

• Sinônimo(s): 3-O-sulfo-D-galactosyl-β1-1′-N-[2"(R)-hydroxystearyl]-D-erythro-sphingosine (ammonium salt), (synthetic)
• Fórmula empírica (Notação de Hill): C₄₂H₈₄N₂O₁₂S
• Número CAS: 2260670-26-4
• Peso molecular: 841.19
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Formulário: powder
• embalagem: pkg of 1 × 1 mg (860842P-1mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 860842P
• tipo de lipídio: sphingolipids
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC([C@H](O)CCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H]([C@H]1CO)O.[NH4+]

Descrição

Descrição geral

18:0(2R-OH) Sulfo GalCer, also known as 3-O-sulfo-D-galactosyl-β1-1′-N-[2"(R)-hydroxystearyl]-D-erythro-sphingosine, is a sulfatide that belongs to the class of sphingolipids. It is highly found in membranous myelin sheath formed around nerve axons in gangliosides. This sulfated galactosylceramide contains 3-O-sulfo-β-d-galactose moiety linked to transmembrane-embedded unique ceramide containing 18C long chain base fatty acid (stearic acid) with 2′-hydroxyl group in R configuration.

Ações bioquímicas/fisiológicas

Sulfatides are involved in various cellular processes such as protein trafficking, signal transduction and neuronal cell differentiation. Accumulation of sulfoglycolipids (mainly sulfo-galactosylceramide, S-GalCer) in lysosomes, due to the inherited deficiency of arylsulfatase A (ASA), causes metachromatic leukodystrophy in humans. In mice, deficiency of sulfatide causes paralysis due to demyelination.

Embalagem

5 mL Amber Glass Screw Cap Vial (860842P-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Ponto de fulgor (°F): No data available
• Ponto de fulgor (°C): No data available